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  1. PSA levels between 4.0 and 10.0 ng/mL might suggest the possibility of prostate cancer (in about 25 percent of cases) or BPH. The PSA levels above 10.0 ng/mL should be urgently discussed with your doctor because these are associated with a 50 percent chance of having prostate cancer. The levels from 0.25 ng/mL to 4 ng/mL along with symptoms of ...

  2. Mar 18, 2024 · That’s because the range of what’s normal varies by age. Technically, someone with any PSA level can have prostate cancer; that’s not the only thing we look at when assessing a patient. Generally speaking, though, PSA levels for men who are: Age 60 or older: should be at or below 4.0 mg/mL. Age 59 or younger: should be at or below 2.5 mg/mL.

  3. The Canadian Urological Association (CUA) does not provide professional medical advice, diagnosis or treatment and cannot respond to requests for direct feedback, specific patient information or physician referrals. You should first always seek the advice of your urologist, physician and other qualified health provider with any questions ...

  4. Apr 8, 2024 · Myth: PSA screening reduces prostate cancer mortality by about 1 in 1,000. PSA screenings have reduced deaths significantly more than 1 in 1,000. “This number is frequently cited, and it makes it look like the benefits are small, but it is based on a misunderstanding of a well-known trial,” Dr. Vickers says.

    • Overview
    • What is the typical range for PSA by age?
    • What can affect your PSA level?
    • What can I expect if my PSA levels are high?
    • Takeaway

    Typical PSA levels vary by age. A PSA level that’s higher than typical may indicate prostate cancer, but not always. Likewise, a low PSA level doesn’t necessarily mean you don’t have prostate cancer.

    Your prostate-specific antigen (PSA) levels should usually be pretty low. PSA is a protein your prostate gland produces. High levels of PSA circulating in your blood may indicate prostate cancer.

    Experts consider PSA levels below 4 nanograms per milliliter (ng/mL) to be typical for most people. Anything higher may indicate that you have cancerous cells in your prostate gland. But this isn’t always the case.

    What doctors consider a typical PSA level may vary based on your age and other factors. When diagnosing prostate cancer, a PSA test is just one of several diagnostic tools a doctor will use.

    Read on to learn more about how your PSA levels may differ based on your age. We’ll also review other factors that may affect your PSA levels and what to expect if your PSA test results are high.

    Language matters

    PSA levels can vary based on your age. There’s no official guidance on what a typical range is and what the upper limit should be for further testing.

    The recommended upper limits for PSA levels by age are as follows:

    Even if you’re not at the upper limit, a doctor may still order further testing based on your symptoms, history, or other factors.

    It’s also important to note that experts generally agree upon these values for white people. Research suggests that healthy Black people have higher PSA levels than white or Hispanic people.

    Some factors that can affect your PSA levels (and even make them appear lower on a PSA test) include:

    •the size of your prostate gland

    •having had a recent prostate biopsy

    •having had a recent procedure to look inside your bladder or remove bladder cancer (cystoscopy)

    •having an ejaculation within the 48 hours before testing

    •smoking or tobacco use

    If your PSA levels are high, a doctor may order another test to compare the results and confirm that your PSA levels are actually high. If you take two PSA tests that show high levels, the doctor may ask to perform a digital rectal exam (DRE) to feel your prostate gland for any lumps or abnormal tissue.

    If they don’t find any abnormal tissue or growths, the doctor will likely ask you to take another PSA test in a few months and recommend another DRE to keep observing your prostate gland. This process is called watchful waiting (or active surveillance). It helps the doctor closely monitor your prostate for any changes.

    If the doctor finds irregular tissue or growths, they may order imaging tests to get a detailed view of your prostate and the surrounding area. This can include a prostate ultrasound or magnetic resonance imaging (MRI).

    In some cases, the doctor may also take a prostate biopsy (or tissue sample) to test your prostate tissue for the presence of cancerous cells. This involves inserting a needle into your prostate through your rectum or perineum to extract a small amount of tissue they can look at using a microscope.

    Imaging and biopsy can help the doctor confirm a diagnosis of prostate cancer. Imaging along with PSA level results can also help determine what stage of prostate cancer you’re in:

    •Stage 1: Cancerous cells are found on only one side of your prostate.

    Doctors usually consider PSA levels below 4 ng/mL typical if you’re between 40–70 years old. But what’s typical may vary by age and other individual factors.

    Still, even low PSA levels may not accurately indicate whether or not you have prostate cancer. Your PSA levels are just one of several measurements a doctor might use to diagnose prostate cancer.

  5. The PSA blood test is a simple way to check your prostate health. It can detect issues early when they are most treatable. Working together with your doctor, you can weigh the pros and cons of prostate cancer screening. This team approach, known as shared decision-making, puts your needs and preferences at the center of the decision, making ...

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  7. A prostate-specific antigen (PSA) test measures the amount of PSA in the blood. PSA is a protein made by prostate cells. The prostate is part of the male reproductive and urinary systems. PSA is mostly found in semen, which is also made in the prostate, but small amounts of PSA can also be found in the blood.

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  2. Learn About A Medication For Your Active PsA. Get Information On A Once-Daily Pill Now. Are PsA Symptoms Still Affecting You? It Could Be Time For A Treatment Plan Change.

  3. Stay Up-to-Date About Testing & Precision Medicine for Prostate Cancer. Sign Up Today. HCPs View Info About BRCA+ mCRPC Treatment for Your Patient. See Dosing Modifications.

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