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  1. The Cancer Moonshot is mobilizing efforts toward achieving two clear goals that the President and First Lady set: To prevent more than 4 million cancer deaths by 2047 and to improve the...

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      FACT SHEET: President Biden Details Cancer Moonshot Progress...

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  2. Jun 1, 2023 · Addeddate 2023-06-02 01:02:48 Duration 482 Identifier actonma-White_House_Cancer_Moonshot_with_Dr._Catharine_Young Run time 00:08:02

    • Improving Immunotherapy
    • Childhood Cancers
    • Tumor Atlases
    • Cancer Prevention and Early Detection
    • Engaging with Patients
    • Greater Collaboration
    • Enhanced Data Sharing
    • The Future

    In recent years, drugs that enhance the immune system’s ability to detect and kill tumor cells—known as immunotherapy—have benefited many patients with certain types of cancer, including hard-to-treat cancers like melanoma and lung cancer. The Blue Ribbon Panel made recommendations to expand the benefits of immunotherapy for children and adults wit...

    Researchers have learned that the major drivers of pediatric cancers are rogue proteins known as fusion oncoproteins. Developing a better understanding of how these proteins function and how they transform normal cells into cancer cells is critical for advancing progress against pediatric cancer. To implement the Blue Ribbon Panel’s recommendation ...

    Another Moonshot recommendation is to generate human tumor atlases that describe the various cellular, structural, and molecular characteristics of human cancers over time. Toward this end, the Human Tumor Atlas Network (HTAN) is creating detailed spatial and temporal “maps” of a variety of cancers that will be used to investigate how cancer might ...

    The Blue Ribbon Panel recommended investing in research to reduce cancer risk and cancer disparities through the expanded use of proven strategies for cancer prevention and early detection. The Cancer Center Cessation Initiative was created to address this recommendation, helping cancer centers build and implement sustainable tobacco cessation trea...

    The Moonshot has aimed to modernize how patients are involved in clinical cancer research, which is a critical driver of cancer progress. One approach pioneered by the Moonshot has been to establish patient-centric networks to improve outreach and engagement. For example, the Participant Engagement and Cancer Genome Sequencing Research Network is u...

    As these examples illustrate, enhanced collaboration among investigators—and patients and advocates—can be a valuable accelerant of research progress. To foster greater collaboration, many Moonshot programs work as interconnected networks, designed to leverage the strengths and expertise of all investigators and partners involved. An explicit goal ...

    The Moonshot embraced an approach of “radical data sharing.” Through the Moonshot data-sharing policy, new findings and underlying data from all Moonshot-funded studies are made publicly available as promptly as possible. To facilitate dissemination of new findings, all publications of Moonshot-supported research must be published in open-access fo...

    As these examples illustrate, the Cancer Moonshot’s strategies and investments are indeed moving cancer research forward. Successful programs are in place to deliver important advances by 2023, the final year of dedicated Moonshot funding. To maintain the pace of progress established since the Moonshot’s inception, we need to ensure a smooth transi...

  3. Cancer: The Emperor of All Maladies matches the epic scale of the disease, reshaping the way the public sees cancer and stripping away some of the fear and misunderstanding that has long ...

  4. Jul 7, 2021 · The architects of the Moonshot understood that progress in cancer research requires quick dissemination of data and findings. To ensure that results of Moonshot studies are promptly and broadly accessible, NCI requires that all Moonshot-supported publications be made publicly available immediately.

    • Norman E. Sharpless, Dinah S. Singer
    • 2021
  5. Download the complete report. The BRP report describes 10 transformative research recommendations for achieving the Cancer Moonshot's goal of making a decade's worth of progress in cancer prevention, diagnosis, and treatment in just 5 years. establish a network for direct patient involvement.

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  7. Learn how the Cancer Moonshot is taking an all-of-government approach to improve the experience of everyone who is touched by cancer. The Cancer Moonshot was launched in 2016 to accelerate scientific discovery in cancer research, foster greater collaboration, and improve the sharing of cancer data.

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