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Dr. Jim Allison, recipient of the 2018 Nobel Prize in Physiology or Medicine, is helping MD Anderson Cancer Center lead the fight to end cancer. Learn more a...
Mar 31, 2020 · Allison received the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor. Dr. Allison is the first MD Anderson scientist to receive the world’s most preeminent award for outstanding discoveries in the fields of life sciences and medicine. He started ...
- Early Life, South Texas
- The University of Texas at Austin: Undergraduate and Graduate Training
- Scripps Clinic and Research Foundation: 1974–77
- The University of California, Berkeley: 1984–2004
- Memorial Sloan-Kettering Cancer Center: 2004–2012
- University of Texas MD Anderson Cancer Center: 2012–Present
I was born in 1948 in Alice, a small farming and oil town in the brush country of the Rio Grande Valley in South Texas. Those early years in Alice shaped who I would later become. Being in Texas, the whole town, including my two older brothers, was obsessed with football. But, I learned from a young age that being crushed under a pile of big sweaty...
I enrolled at UT Austin in the summer session immediately after high school graduation. Due to my summers in Austin, I never thought of going anywhere else. In accordance with my father’s hopes, I began as a premed student. However, I became dissatisfied with the rote memorization required in some of the pre-med courses. At the beginning of my seco...
Professors Mandy and Kitto helped me get a post-doctoral appointment in Ralph Reisfeld’s laboratory at Scripps Clinic in La Jolla, California. I felt that this was a great choice because Scripps was a hotbed of research in immunology, and because Reisfeld had recently reported the isolation and initial characterization of human histocompatibility (...
UC Berkeley is a marvelous place, teeming with bright, inventive people seeking knowledge. My time at UC Berkeley was notable for my interactions with many wonderful colleagues and students. It was a time of discovery, collegiality, long days working in the lab, and long nights partying with everyone in the lab. Max Krummel described it best by say...
I arrived in Manhattan during the summer of 2004 with most of my laboratory intact. Over the next 8 years, I did my best to help Thomas Kelly hire a cadre of the best immunologists that we could, and I feel that we succeeded in building a truly spectacular group of basic immunologists involved in a variety of studies relevant to the cancer problem....
At MSKCC, my lab had continued exploring ways in which to improve anti-tumor responses with anti-CTLA-4 treatment. We performed many experiments including combinations with chemotherapy, radiation therapy, cryoablation and with other immune checkpoint agents. After anti-CTLA-4 was shown to have some clinical success in the early clinical trials, ma...
Nov 18, 2019 · James "Jim" Allison, Ph.D., is chair of Immunology and executive director of the Immunotherapy platform at MD Anderson. He was awarded the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor. MD Anderson depends on the generous support of donors to ...
Oct 1, 2018 · Targets for immune-boosting drugs: Allison’s work on CTLA-4. In 1996, Allison and his team found that CTLA-4 works like a silencing switch on T cells – preventing them from assembling an army of supporting immune cells to attack foreign invaders. And in landmark work, the team showed early signs of how this knowledge could transform cancer ...
Oct 1, 2018 · 2014 Canada Gairdner Award Laureate Dr. James P. Allison was awarded the 2018 Nobel Prize in Medicine this morning at an announcement held ...
Interview, December 2018. Interview with Medicine Laureate James P. Allison on 6 December 2018 during the Nobel Week in Stockholm, Sweden. Read the interview. James P. Allison answers the following questions (the links below lead to clip on YouTube): 00:06 What triggered your interest in researching a new cancer therapy?
