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May 10, 2024 · As reported in 2020, traumatic injury due to accident is the most common cause of amputation, accounting for 92.9% of 122 240 patients with upper limb amputation and 76.3% of 49 516 patients with lower limb amputation. 11 Therefore, it is possible to conduct research on patients with amputation due to traumatic causes in Korea using subjects from the general population instead of being limited ...
- Introduction
- Pathophysiology
- Systemic Influences
- Hemodynamic Factors Operating Proximal to The Amputation
- Cardiovascular Risk Estimate in Traumatic Leg Amputees
- Future Studies
Post-traumatic lower limb amputees are subject to increased morbidity and mortality from cardiovascular disease, discussed in the literature over the past four decades.1–11However, risk factors for this amplified morbidity and the involved pathophysiologic mechanisms have not been comprehensively studied. The story begins when the Veterans Administ...
The causes for an excess in cardiovascular morbidity and mortality among traumatic lower limb amputees are not well understood. Systemic influences and regional hemodynamic effects may be involved in this process, though neither has been comprehensively investigated.7–14 Insulin resistance, psychological stress and patients’ deviant behaviors are f...
A pathogenic role for insulin resistance in the excess cardiovascular morbidity among traumatic lower limb amputees was suggested by Rose et al.12 In their study of 19 bilateral above-knee amputees from the Vietnam war in comparison with 12 age-matched unilateral below-elbow amputees, Rose observed significantly more hypertension and obesity in abo...
Proximal leg amputation is associated with greater risk to develop cardiovascular diseases than distal amputation, and bilateral amputation with greater risk than unilateral amputation. Hemodynamic abnormalities, resulting from perturbed arterial flow proximal to the amputation site, are assumed to explain this incremental risk related to the site ...
Currently, two algorithms for assessing cardiovascular risk are recommended in the National Cholesterol Education Program Adult Treatment Pannel III Guidelines.54 The first algorithm involves counting major risk factors based on an equation derived from the Framingham Heart Study. The second algorithm identifies the metabolic syndrome. These predic...
An improved assessment of coronary risk in traumatic leg amputees, so as to guide prophylactic and therapeutic measures, is required. This aim may be advanced via large-scale studies where potential risk factors are linked to cardiovascular events. In addition to traditional and novel risk factors, assessment of psychological stress and psychologic...
- J.E. Naschitz, R. Lenger
- 2008
Sep 5, 2018 · It is well-known that the risk of cardiac disease is increased for those with lower-limb amputations, likely as a result of the etiology of the amputation. Using a longitudinal population-based dataset, we examined the association between transfemoral amputation (TFA) status and the risk of experiencing a major cardiac event for those undergoing either dysvascular or traumatic amputations.
- Benjamin F. Mundell, Marianne T. Luetmer, Hilal Maradit Kremers, Sue Visscher, Kurtis M. Hoppe, Kent...
- 2018
Oct 12, 2024 · Amputation is surgery to remove all or part of a body appendage, usually a limb or extremity (an arm, leg, hand or foot). You might need surgery to amputate a body part if it’s too sick or injured to save and it endangers other parts. You might also need surgery if you lose a body part in a traumatic accident.
Oct 12, 2022 · When blood flow isn’t adequate, the cells within the limb don’t get oxygen from the bloodstream, resulting in tissue beginning to die. Diabetes: Another disease that causes a loss of limbs is diabetes. Diabetes causes amputation because just like PAD, it can impact your blood flow. In fact, roughly 54% of all surgical amputations stem from ...
May 23, 2022 · Critical limb ischemia is a severe stage of peripheral artery disease, in which you have significant blockages in the blood flow to your arms, legs or feet. This increases your risk of heart complications. Some people need an amputation to treat critical limb ischemia. The sooner you get treatment, the higher your chances of a good outcome.
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Jul 3, 2020 · Background: Peripheral artery disease (PAD) is associated with increased risk of mortality, cardiovascular morbidity, and major amputation. Data on major amputation from a large randomized trial that included a substantial cohort of patients without critical limb ischemia (CLI) have not been described. The objective was to describe the incidence and types of amputations in the EUCLID trial ...
