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  1. Feb 2, 2022 · The major causes of classic FUO are infections, cancers, autoinflammatory or autoimmune conditions, and miscellaneous causes. 3 A review of all infections causing FUO is not...

  2. Fever of unknown origin (FUO) was originally defined by Petersdorf and Beeson as an illness of more than 3 weeks’ duration, with fever greater than 38.3 °C (101 °F) on several occasions, the cause of which is uncertain after 1 week of in-hospital investigations.

  3. Aug 14, 2023 · The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous.

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021
  4. Jul 9, 2024 · Infections are the most common cause of FUO. In patients with HIV infection, opportunistic infections (eg, tuberculosis; infection by atypical mycobacteria, disseminated fungi, or cytomegalovirus) should be sought.

    • Larry M. Bush
  5. Fever of unknown origin (FUO) can result from infection with a variety of bacteria, viruses, parasites and fungi. The diagnosis of a bacterial infection can often be made on culture of suitable samples but may require the detection of specific antibodies or bacterial DNA for organisms that are difficult to grow.

  6. Fever of unknown origin (FUO) was originally characterised in 1961 by Petersdorf and Beeson as a disease condition of temperature exceeding 38.3 °C on at least three occasions over a period of at least three weeks, with no diagnosis made despite one week of inpatient investigation.

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  8. Common causes of FUO include infections, malignancies, noninfectious inflammatory disease (e.g., vasculitides, granulomatous disease, connective tissue diseases),...

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