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  1. Fever of unknown origin (FUO) was originally defined by Petersdorf and Beeson as an illness of more than 3 weeks’ duration, with fever greater than 38.3 °C (101 °F) on several occasions, the cause of which is uncertain after 1 week of in-hospital investigations.

  2. Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient investigations. 2...

  3. Jul 9, 2024 · Fever of unknown origin (FUO) is body temperature 38.3° C (≥ 101° F) rectally that does not result from transient and self-limited illness, rapidly fatal illness, or disorders with clear-cut localizing symptoms or signs or with abnormalities on common tests such as chest radiograph, urinalysis, or blood cultures.

    • Larry M. Bush
  4. Common causes of FUO include infections, malignancies, noninfectious inflammatory disease (e.g., vasculitides, granulomatous disease, connective tissue diseases),...

  5. Aug 14, 2023 · The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous.

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021
  6. Aug 31, 2018 · Common causes include: pulmonary embolism. enterocolitis. sinusitis. deep vein thrombosis. septic thrombophlebitis, a type of inflammation that affects the veins. Immune-deficient FUO occurs in...

  7. Fever of unknown origin (FUO) can result from infection with a variety of bacteria, viruses, parasites and fungi. The diagnosis of a bacterial infection can often be made on culture of suitable samples but may require the detection of specific antibodies or bacterial DNA for organisms that are difficult to grow.

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