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  1. The first rule is that “all living organisms are made of cells“, the second is that “the cell is the smallest structural and functional biological unit that constitutes a living organism”, and the third is that “every cell is derived from another cell” [2] (Figure 1).

  2. Apr 19, 2021 · Epigenetics is the study of changes in gene activity that can be transmitted through cell divisions but cannot be explained by changes in the DNA sequence. Epigenetic mechanisms are central to gene regulation, phenotypic plasticity, development and the preservation of genome integrity.

    • Alyson Ashe, Vincent Colot, Benjamin P Oldroyd
    • 2021
  3. Jul 18, 2013 · They are called epigenetic regulation and include chromatin remodeling through changes in DNA and histones as well as regulation by miRNAs and asRNA. Furthermore, it was observed that the amount of protein far exceeds the number of genes described.

    • Sandra Ramírez-Clavijo, Gladis Montoya-Ortíz
    • 2013/07/18
    • 2013
  4. Jun 19, 2024 · The evolution of the modern human brain was accompanied by distinct molecular and cellular specializations, which underpin our diverse cognitive abilities but also increase our susceptibility to...

  5. Synthetic gene regulatory circuits have been made that can generate unique and desired outcomes. Can synthetic metabolic circuits be made to accomplish similar outcomes for gene expression? Feedback repression provides gene regulation with the ability to adapt to variable metabolic conditions.

  6. Oct 18, 2023 · Epigenetic information contributes to embryonic development by informing cells about their past, present, and future. It provides a molecular memory of decisions made and of past conditions encountered, with early events integrated into the genome as chemical marks and stably propagated.

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  8. Jul 25, 2016 · What these phenomena all have in common is cellular memory — the maintenance of an activity state of a gene once it is triggered by stress, a change in gene expression, a developmental signal, an environmental cue, or the production of a small RNA.