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  1. Oct 31, 2016 · The two major interfaces separating brain and blood have different primary roles. The choroid plexuses secrete cerebrospinal fluid into the ventricles, accounting for most net fluid entry to the brain. Aquaporin, AQP1, allows water transfer across the apical surface of the choroid epithelium; another protein, perhaps GLUT1, is important on the basolateral surface. Fluid secretion is driven by ...

    • Stephen B. Hladky, Margery A. Barrand
    • 2016
  2. May 31, 2023 · Brain cell structure is a key determinant of neural function that is frequently altered in neurobiological disorders. Following the global loss of blood flow to the brain that initiates the postmortem interval (PMI), cells rapidly become depleted of energy and begin to decompose. To ensure that our methods for studying the brain using autopsy ...

    • What Is White Matter Disease?
    • What Is White Matter?
    • Who Does White Matter Disease Affect?
    • How Common Is White Matter Disease?

    White matter disease is an umbrella term for changes and damage to your brain’s white matter — the nerve fibers in your brainthat connect different areas of your brain to each other and to your spinal cord like highways. You can also get white matter disease, also called cerebral small vessel or microvascular disease, from aging and blood vesselcha...

    White matter is made up of a large network of nerve fibers (axons) in your brain that allows the exchange of information and communication between different areas of your brain. It’s called “white matter” because the nerve fibers are covered in a protective sheath called myelin, which gives the tissue its white color. The surface and deep areas of ...

    White matter disease can affect anyone, but it’s more common in people 60 years of age and older and in people who have cardiovascular disease. While a few white matter lesions can be seen with a brain MRI in younger people with conditions like migraine, getting older and having more uncontrolled risk factors for cardiovascular disease increases yo...

    White matter disease is common. It’s present in more than half of the population of people who are 60 years old.

  3. Apr 12, 2021 · This Review examines the molecular mechanisms underlying transmembrane fluid movement in individual cells (neurons and glia) and across brain barriers (blood–brain barrier (BBB) and blood–CSF ...

    • Nanna MacAulay
    • macaulay@sund.ku.dk
    • 2021
  4. May 17, 2023 · Abstract. Cerebrospinal fluid plays a crucial role in protecting the central nervous system (CNS) by providing mechanical support, acting as a shock absorber, and transporting nutrients and waste products. It is produced in the ventricles of the brain and circulates through the brain and spinal cord in a continuous flow.

    • 10.3390/biomedicines11051461
    • 2023/05
    • Biomedicines. 2023 May; 11(5): 1461.
  5. Nov 3, 2010 · Cells that remain in the epidermal layer are transformed into one of two types of ectodermal layer stem cells. Epidermal ectodermal stem cells will give rise to structures such as skin, nails, and sweat glands, while neurectodermal stem cells will give rise to the brain and central nervous system. The neuroectodermal stem cells are the neural ...

  6. Nov 20, 2017 · Microglia and brain macrophages. Myeloid cells in the brain. Microglia constitute 5–10% of total brain cells and are the only true CNS parenchymal macrophages 28. Microglia and perivascular ...

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