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- Key components of the stress system are the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system (ANS), which interact with other vital centers in the central nervous system (CNS) and tissues/organs in the periphery to mobilize a successful adaptive response against the imposed stressor (s).
Apr 3, 2024 · Over time, repeated activation of the stress response takes a toll on the body. Research suggests that chronic stress contributes to high blood pressure, promotes the formation of artery-clogging deposits, and causes brain changes that may contribute to anxiety, depression, and addiction.
- hhp_info@health.harvard.edu
May 7, 2024 · The physiological responses of the body to stress have significant implications in various clinical applications, such as managing healthy patients, patients with hypoadrenalism undergoing surgery, and understanding the relationship between lifestyle changes and the stress response.
- Brianna Chu, Komal Marwaha, Terrence Sanvictores, Derek Ayers
- 2024/05/07
- 2019
Nov 9, 2023 · The hypothalamus in the brain is in charge of the stress response. When a stress response is triggered, it sends signals to two other structures: the pituitary gland and the adrenal medulla . The fight or flight response produces these short-term responses via the Sympathomedullary Pathway (SAM).
Oct 17, 2020 · The adaptive response of each individual to stress is determined by a multiplicity of genetic, environmental, and developmental factors. Changes in the ability to effectively respond to stressors (e.g. inadequate, excessive and/or prolonged reactions) may lead to disease.
- Constantine Tsigos, Ioannis Kyrou, Eva Kassi, George P. Chrousos
- 2020/10/17
- 2016
Jul 8, 2022 · The SNS is involved in the body’s stress response. It releases the stress hormones adrenaline and cortisol to help with the “fight or flight” response. When the acute stress is over, the parasympathetic nervous system (PNS) helps your body return to its normal state. 3
As has been discussed in this review, various factors, for example, hormones, neuroendocrine mediators, peptides, and neurotransmitters are involved in the body's response to stress. Many disorders originate from stress, especially if the stress is severe and prolonged.
Neural circuits within the limbic system that regulate fear, executive function, learning, and memory are particularly sensitive to chronic stress, and recent findings emphasize important roles of the cell- and pathway-specific effects of stress.
