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  1. Jun 17, 2021 · But the bottom line was that from a genetic standpoint, the prostate cancer cell line was not a representative surrogate for what happens in a typical human with prostate cancer. The investigators found that, using a 0-1 scoring method, cell lines had, on average, lower scoring alignment to atlas data than tumoroids and xenografts.

  2. Apr 24, 2019 · Summary. Like all cells, cancer cells need nutrients to grow. Sugar is one important fuel, but it’s far from cancer’s only requirement. Current research is aimed at targeting cancer’s dependence on the amino acid glutamine as a weakness. In 1955, an American doctor named Harry Eagle made a surprising discovery about cancer cells growing ...

  3. Jun 18, 2021 · Most cancer cells grown in a dish have little in common with cancer cells in people, research finds. ScienceDaily . Retrieved November 17, 2024 from www.sciencedaily.com / releases / 2021 / 06 ...

  4. Mar 7, 2016 · To determine where cells, including those in tumors, were getting the building blocks they needed, the researchers grew several different types of cancer cells and normal cells in culture dishes. They fed the cells different nutrients labeled with variant forms of carbon and nitrogen, allowing them to track where the original molecules ended up ...

  5. Jun 1, 2018 · In this review, we will provide an overview of available reprogramming methods of cancer cells and describe how cancer-derived stem cells have been used to characterize effects of defined molecular alterations in specific cell types. We also describe the “disease in a dish” model developed to study genetic cancer syndromes.

    • Mo Liu, Jian Tu, Jian Tu, Julian A Gingold, Celine Shuet Lin Kong, Dung-Fang Lee
    • Am J Cancer Res. 2018; 8(6): 944-954.
    • 2018
    • 2018
  6. Apr 1, 2021 · Starving Cancer Stem Cells. Using mouse models and cells growing in a dish, Dr. Finley and her colleagues in the Elaine Fuchs Lab at The Rockefeller University found that the amount of an amino acid called serine in a stem cell’s environment determines its decision to keep dividing in its current form — or to differentiate and grow up.

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  8. For many years now, researchers have studied motility usually by growing cancer cells in a Petri dish and observing how they move about. When cultured on a substrate in a dish, cancer cells typically flatten and move in a slow, seemingly random fashion by pulling themselves along by their leading edges.

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