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Jun 17, 2021 · But the bottom line was that from a genetic standpoint, the prostate cancer cell line was not a representative surrogate for what happens in a typical human with prostate cancer. The investigators found that, using a 0-1 scoring method, cell lines had, on average, lower scoring alignment to atlas data than tumoroids and xenografts.
Apr 24, 2019 · In 1955, an American doctor named Harry Eagle made a surprising discovery about cancer cells growing in a dish: They required ridiculous amounts of glutamine. Without this chemical, the cells would stop growing and eventually die, despite having all the other known requirements for life.
Jun 18, 2021 · Most cancer cells grown in a dish have little in common with cancer cells in people, research finds. ScienceDaily . Retrieved November 17, 2024 from www.sciencedaily.com / releases / 2021 / 06 ...
Apr 1, 2021 · Starving Cancer Stem Cells. Using mouse models and cells growing in a dish, Dr. Finley and her colleagues in the Elaine Fuchs Lab at The Rockefeller University found that the amount of an amino acid called serine in a stem cell’s environment determines its decision to keep dividing in its current form — or to differentiate and grow up.
Jun 18, 2021 · The investigators say their work adds to evidence that cancer cell lines grown in the laboratory have less parity with their human source because of the complex differences between a human cell's ...
Jun 1, 2018 · In contrast, differentiated cells from colorectal cancer cell reprogrammed iPCCs showed increased sensitivity to anti-cancer drugs compared to parental cells . These data suggest that the degree of similarity between cancer-derived iPCC-derived cells and patient cancer cells is likely to depend on both the “parental” cancer cell type as well as the lineage to which the iPCC is differentiated.
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treatments for conditions. Among the most widely used cancer research models are cell lines created by extracting cells from human tumors and growing them with various nutrients in laboratory ...
