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Aug 14, 2023 · Development of the skeletal muscle involves the differentiation of myotome cells into myoblasts. This article will discuss the embryological development of the axial skeleton, the appendicular skeleton, and the skeletal muscle, as well as the associated malformations that may occur.
- Danny Ly
- Medical Content Validation
Satellite cells help to repair skeletal muscle cells. Smooth muscle tissue can regenerate from stem cells called pericytes, whereas dead cardiac muscle tissue is replaced by scar tissue. Aging causes muscle mass to decrease and be replaced by noncontractile connective tissue and adipose tissue.
- Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
- 2019
Define fibrosis. Explain which muscle has the greatest regeneration ability. Most muscle tissue of the body arises from embryonic mesoderm. Paraxial mesodermal cells adjacent to the neural tube form blocks of cells called somites.
During embryogenesis, skeletal muscle forms in the vertebrate limb from progenitor cells originating in the somites. These cells delaminate from the hypaxial edge of the dorsal part of the somite, the dermomyotome, and migrate into the limb bud, ...
Mammalian skeletal muscles derive from mesoderm segments flanking the embryonic midline. Trunk muscles derive from the paraxial somitic mesoderm and serve in locomotion. Head muscles derive from the pre-chordal and paraxial head mesoderm (referred as cranial mesoderm) and control mastication, breathing, eye movement and facial expression.
- Hung Ping Shih, Michael K. Gross, Chrissa Kioussi
- 10.1016/j.acthis.2007.08.004
- 2008
- 2008
The myotome cells producing the myogenic bHLH proteins are the myoblasts—committed muscle cell precursors. Experiments with chimeric mice and cultured myoblasts showed conclusively that these cells align together and fuse to form the multinucleated myotubes characteristic of muscle tissue.
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May 1, 2023 · The effects typically present as skeletal muscle with weakness in the pelvic girdle muscles that progressively involve other muscles. Muscle biopsy may show muscle replaced by fat. DMD affects cardiac myocytes to cause a dilated cardiomyopathy, which is typically the cause of death.
