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1. • • Prolonged fever of 38.3°C or higher for at least 3 weeks’ duration has been termed fever of unknown origin if unexplained after preliminary investigations.
     www.amjmed.com/article/S0002-9343(21)00526-X/fulltext

     Fever of Unknown Origin (FUO) – A Call for New Research ...

2. www.aafp.org › pubs › afpFever of Unknown Origin in Adults | AAFP

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   Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The...

   • Roth and Basello

     Fever of unknown origin (FUO) in adults is defined as a...

   • AAFP

     Articles Fever of Unknown Origin in Adults. Aïsha David,...

   • Hersch and Oh

     Zenone T. Fever of unknown origin in adults: evaluation of...

3. www.ncbi.nlm.nih.gov › books › NBK532265Fever of Unknown Origin - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK532265

   Aug 14, 2023 · The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous.

   • Author: Ilona Brown, Nancy A. Finnigan
   • Published: 2023/08/14

   • Publish Year: 2021

4. Videos

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     17:49

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     An Approach to Fever of Unknown Origin (FUO)

     Oct 21, 2020

     78.3K Views

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     37:50

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     Fever/Pyrexia of Unknown Origin (FUO/PUO) Medicine Lecture, Diagnosis, Causes, Harrison NeetPg USMLE

     Dec 9, 2023

     40.2K Views

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     4:37

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     Fever of Unknown Origin (FUO) - Causes. Unexplained Fever, Low grade fever

     Jul 29, 2022

     10K Views

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5. www.uptodate.com › contents › fever-of-unknownFever of unknown origin in adults: Evaluation and management

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   Nov 28, 2023 · Clinicians commonly refer to a febrile illness without an initially obvious etiology as fever of unknown origin (FUO). However, most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

6. www.bmj.com › content › 341Investigating and managing pyrexia of unknown origin in adults

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   Oct 15, 2010 · Classic adult pyrexia of unknown origin is fever of 38.3°C or greater for at least 3 weeks with no identified cause after three days of hospital evaluation or three outpatient visits. Common causes are infections, neoplasms, and connective tissue disorders.

   • Author: George M Varghese, Paul Trowbridge, Tom Doherty

   • Publish Year: 2010

7. www.aafp.org › pubs › afpApproach to the Adult Patient with Fever of Unknown Origin ...

   www.aafp.org › pubs › afp

   Fever of unknown origin (FUO) in adults is defined as a temperature higher than 38.3°C (100.9°F) that lasts for more than three weeks with no obvious source despite appropriate...

8. www.healthline.com › health › fever-of-unknown-originAbout Fever of Unknown Origin - Healthline

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   Aug 31, 2018 · A fever of unknown origin (FUO) is a fever of at least 101°F (38.3°C) that lasts for more than three weeks or occurs frequently without explanation. Even when a doctor can’t determine the...

9. People also ask

   What is a fever of unknown origin?

   • Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is broad but is typically categorized as infection, malignancy, noninfectious inflammatory disease, or miscellaneous.

   Fever of Unknown Origin in Adults - AAFP

   www.aafp.org/pubs/afp/issues/2022/0200/p137.html

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   What causes fever of unknown origin (FUO)?

   • The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous. Noninfectious Inflammatory Causes of FUO Infectious Causes of FUO

   Fever of Unknown Origin - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK532265/

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   What is the epidemiology of fever of unknown origin (FUO)?

   • Epidemiology of fever of unknown origin (FUO) varies based on etiology of fever, age group, geography, environmental exposure, and immune/HIV status. In developing countries, an infectious etiology of FUO is most prevalent whereas, in developed countries, FUO is likely due to non-infectious inflammatory disease.

   Fever of Unknown Origin - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK532265/

   See all results for this question

   What is a recurrent fever of unknown origin (FUO)?

   • Recurrent fever of unknown origin (FUO): aseptic meningitis, hepatosplenomegaly, pericarditis and a double quotidian fever due to juvenile rheumatoid arthritis (JRA). [Heart Lung. 2012] Fever of unknown origin (FUO). II. Diagnostic procedures in a prospective multicenter study of 167 patients. The Netherlands FUO Study Group.

   Fever of Unknown Origin - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK532265/

   See all results for this question

   Can Empiric antimicrobial therapy treat fever of unknown origin?

   • Empiric antimicrobial therapy has not been shown to be effective in the treatment of fever of unknown origin and therefore should be avoided except in patients who are neutropenic, immunocompromised, or critically ill. Fever of unknown origin (FUO) in adults poses one of the greatest diagnostic challenges in medicine.

   Fever of Unknown Origin in Adults - AAFP

   www.aafp.org/pubs/afp/issues/2022/0200/p137.html

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   How many cases of fever of unknown origin are there?

   • Mansueto P, Di Lorenzo G, Rizzo M, Di Rosa S, Vitale G, Rini G, Mansueto S, Affronti M. Fever of unknown origin in a Mediterranean survey from a division of internal medicine: report of 91 cases during a 12-year-period (1991-2002). Intern Emerg Med. 2008 Sep;3(3):219-25. [PubMed]

   Fever of Unknown Origin - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK532265/

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10. www.nejm.org › doi › fullFever of Unknown Origin | New England Journal of Medicine

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    Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient...