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      • Fever is a common presenting complaint in children. Most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis. Fever of unknown origin (FUO) refers to a prolonged febrile illness without an established etiology despite thorough evaluation.
      www.uptodate.com/contents/fever-of-unknown-origin-in-children-evaluation
  1. Jan 23, 2023 · Fever of unknown origin (FUO) refers to a prolonged febrile illness without an established etiology despite thorough evaluation. An approach to the evaluation of FUO in children will be reviewed here.

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  2. Dec 13, 2022 · Fever is a common presenting complaint in children, accounting for nearly one-third of pediatric outpatient visits in the United States [1]. Common etiologies of FUO in children will be discussed below.

  3. Feb 29, 2024 · In general, a fever means a temperature above 100.4°F (38°C). You might get slightly different numbers depending on how you take your child's temperature – oral (mouth), axillary (armpit), ear, forehead, or rectal.

  4. Fever that occurs daily for ≥ 2 weeks and for which initial cultures and other investigations fail to yield a diagnosis is considered fever of unknown origin (FUO). Potential categories of causes (see Table: Some Common Causes of Fever in Children) include localized or generalized infection, connective tissue disease, and cancer.

  5. Aug 14, 2023 · Fever of unknown origin (FUO) was first described by Dr. Petersdorf and Dr. Beesom in 1961. FUO was defined as a temperature of 101 degrees Fahrenheit (38.3 degrees Centigrade) or higher with a minimum duration of three weeks without an established diagnosis after an intensive one-week investigation in the hospital.

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021
  6. Fever of unknown origin (FUO) is defined as fever lasting at least 3 weeks without an apparent source after 1 week of investigation. The cause of FUO includes infectious, autoimmune, malignancy, neurologic, genetic, pharmacologic, and iatrogenic.

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  8. Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient...

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