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      • FUO refers to a prolonged febrile illness without an established etiology despite intensive evaluation and diagnostic testing.
      www.uptodate.com/contents/approach-to-the-adult-with-fever-of-unknown-origin?search=fever of unknown origin adult&source=search_result&selectedTitle=1~72&usage_type=default&display_rank=1
  1. Nov 28, 2023 · Clinicians commonly refer to a febrile illness without an initially obvious etiology as fever of unknown origin (FUO). However, most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

  2. Nov 20, 2023 · This topic discusses etiologies of classic fever or unknown origin. Other categories of FUO, not discussed in this topic, include health care-associated FUO, FUO in immunocompromised patients, and travel-associated FUO.

  3. Clinicians commonly refer to a febrile illness without an initially obvious etiology (sometimes called fever without localizing signs) as fever of unknown origin (FUO). This usage is not accurate. Most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

  4. Aug 14, 2023 · Fever of unknown origin (FUO) was first described by Dr. Petersdorf and Dr. Beesom in 1961. FUO was defined as a temperature of 101 degrees Fahrenheit (38.3 degrees Centigrade) or higher with a minimum duration of three weeks without an established diagnosis after an intensive one-week investigation in the hospital.

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021
  5. Jun 10, 2024 · Fever of unknown origin (FUO) and inflammation of unknown origin (IUO) are syndromes commonly used as medical diagnoses. Since the existing literature has a mixture of diagnostic approaches, developing consensus-based recommendations would be helpful for clinicians, researchers, and patients.

  6. Jul 9, 2024 · Fever of unknown origin (FUO) is body temperature 38.3° C (≥ 101° F) rectally that does not result from transient and self-limited illness, rapidly fatal illness, or disorders with clear-cut localizing symptoms or signs or with abnormalities on common tests such as chest radiograph, urinalysis, or blood cultures.

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  8. Feb 1, 2022 · Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is broad but is typically categorized as infection, malignancy, noninfectious inflammatory disease, or miscella ….

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