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  1. Nov 28, 2023 · From the perspective of a practicing clinician, an overarching definition of FUO is fever persisting longer than typical self-limiting conditions (eg, common viral illnesses) in the absence of an identifiable cause despite a reasonable evaluation by an experienced clinician. Many clinical researchers have attempted to more precisely define FUO ...

  2. INTRODUCTION. Clinicians commonly refer to a febrile illness without an initially obvious etiology (sometimes called fever without localizing signs) as fever of unknown origin (FUO). This usage is not accurate. Most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

  3. Nov 20, 2023 · FUO refers to a prolonged febrile illness without an established etiology despite intensive evaluation and diagnostic testing. The most common causes of FUO in adults will be reviewed here. The evaluation and management of the adult with FUO, and the etiology of FUO in children, are discussed separately. (See "Fever of unknown origin in adults ...

  4. Jun 10, 2024 · Fever of unknown origin (FUO) and inflammation of unknown origin (IUO) are syndromes commonly used as medical diagnoses. Since the existing literature has a mixture of diagnostic approaches, developing consensus-based recommendations would be helpful for clinicians, researchers, and patients.

  5. Aug 14, 2023 · Fever of unknown origin (FUO) was first described by Dr. Petersdorf and Dr. Beesom in 1961.[1] FUO was defined as a temperature of 101 degrees Fahrenheit (38.3 degrees Centigrade) or higher with a minimum duration of three weeks without an established diagnosis despite at least one week's investigation in the hospital. This definition was later changed to accommodate technological advances ...

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021
  6. Feb 1, 2022 · Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is broad but is typically categorized as infection, malignancy, noninfectious inflammatory disease, or miscellaneous. Most cases in adults occur because of ...

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  8. sso.uptodate.com › contents › fever-of-unknownUpToDate

    Fever is a common presenting complaint in children, accounting for nearly one-third of pediatric outpatient visits in the United States . Common etiologies of FUO in children will be discussed below. The approach to the child with FUO, FWS, and fever in unique host groups (eg, newborns, neutropenic children) are discussed separately.

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