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  1. www.uptodate.com › contents › fever-of-unknownFever of unknown origin in adults: Evaluation and ... - UpToDate

    Nov 28, 2023 · Clinicians commonly refer to a febrile illness without an initially obvious etiology as fever of unknown origin (FUO). However, most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

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      The approach to the child with FUO, FWS, and fever in unique...

  2. www.uptodate.com › contents › fever-of-unknownFever of unknown origin in adults: Etiologies - UpToDate

    Nov 20, 2023 · FUO refers to a prolonged febrile illness without an established etiology despite intensive evaluation and diagnostic testing. The most common causes of FUO in adults will be reviewed here. The evaluation and management of the adult with FUO, and the etiology of FUO in children, are discussed separately.

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  4. www.uptodate.com › contents › approach-to-the-adultApproach to the adult with fever of unknown origin - UpToDate

    Clinicians commonly refer to a febrile illness without an initially obvious etiology (sometimes called fever without localizing signs) as fever of unknown origin (FUO). This usage is not accurate. Most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

  5. www.ncbi.nlm.nih.gov › books › NBK532265Fever of Unknown Origin - StatPearls - NCBI Bookshelf

    Aug 14, 2023 · Fever of unknown origin (FUO) was first described by Dr. Petersdorf and Dr. Beesom in 1961. FUO was defined as a temperature of 101 degrees Fahrenheit (38.3 degrees Centigrade) or higher with a minimum duration of three weeks without an established diagnosis after an intensive one-week investigation in the hospital.

    • Ilona Brown, Nancy A. Finnigan
    • 2023/08/14
    • 2021

  6. sso.uptodate.com › contents › pathophysiology-andPathophysiology and treatment of fever in adults - UpToDate

    Nov 23, 2022 · Definitions of normal body temperature, the pathophysiology of fever, the role of cytokines, and the treatment of fever in adults will be reviewed here. Fever of unknown origin in adults, drug fever, and the treatment of fever in infants and children are discussed separately.

  7. sso.uptodate.com › contents › fever-of-unknownUpToDate

    The approach to the child with FUO, FWS, and fever in unique host groups (eg, newborns, neutropenic children) are discussed separately. (See "Fever of unknown origin in children: Evaluation".) (See "Fever without a source in children 3 to 36 months of age: Evaluation and management".)

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  9. pubmed.ncbi.nlm.nih.gov › 35166499Fever of Unknown Origin in Adults - PubMed

    Feb 1, 2022 · Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is broad but is typically categorized as infection, malignancy, noninfectious inflammatory disease, or miscella …

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