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- Signal transduction in many cellular processes is accompanied by the feature of adaptation, which allows certain key signalling components to respond to temporal and/or spatial variation of external signals, independent of the absolute value of the signal.
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Jul 18, 2019 · To explore the properties of MIMO systems in biology, we chose to study the dynamics of cyclooxygenase-2 (COX-2), a key enzyme that controls the balance between pro-and anti-inflammatory...
- Erin M. Shockley, Carol A. Rouzer, Lawrence J. Marnett, Eric J. Deeds, Carlos F. Lopez, Carlos F. Lo...
- 2019
Aug 9, 2023 · This paper presents a perspective on Biosignal-Adaptive Systems (BAS) which automatically adapt to user needs by continuously interpreting their biosignals and by providing transparent feedback, thereby keeping the user in the loop.
Feb 2, 2013 · Recent advances in our ability to watch the molecular and cellular processes of life in action—such as atomic force microscopy, optical tweezers and Forster fluorescence resonance energy transfer—raise challenges for digital signal processing (DSP) of the resulting experimental data.
- Max A. Little, Nick S. Jones
- 2013
Mar 14, 2019 · A particular information processing characteristic repeatedly encountered in cellular networks is adapation. Adaptation is the characteristic of a module wherein the output of the module is essentially independent of the input at steady state, even though the input is “connected" to the output.
- Jawahar Krishnan, Ioannis Floros, Ioannis Floros
- 2019
Dec 1, 2021 · Adaptation is a key property of living systems, important also in the engineering of robust systems. •. Incoherent feedforward loops and negative feedback loops are network motifs that underlie many adaptive circuits. •. Biological implementations of these network motifs have since been constructed. Abstract.
- Timothy Frei, Mustafa Khammash
- 2021
Feb 20, 2020 · Cells communicate with the outside world to maintain homeostasis. Here the authors design a synthetic biology DNA-based signalling system AMSsys that responds to the presence of ATP.
Dec 18, 2023 · As synthetic biology permeates society, the signal processing circuits in engineered living systems must be customized to meet practical demands. In this review, the authors outline design ...
