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  1. The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify ...

    • Nucleotide Blast

      PSI-BLAST allows the user to build a PSSM (position-specific...

  2. BLAST (biotechnology) In bioinformatics, BLAST (basic local alignment search tool) [3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.

  3. Aug 3, 2023 · BLAST stands for Basic Local Alignment Search Tool. It is a widely used bioinformatics program that was first introduced by Stephen Altschul et al. in 1990 and has since become one of the most popular tools for sequence similarity search. Basic Local Alignment Search Tool (BLAST). Image Source: NCBI.

  4. Today, one of the most common tools used to examine DNA and protein sequences is the Basic Local Alignment Search Tool, also known as BLAST (Altschul et al., 1990).

  5. BLAST is an acronym for Basic Local Alignment Search Tool and refers to a suite of programs used to generate alignments between a nucleotide or protein sequence, referred to as a “query” and nucleotide or protein sequences within a database, referred to as “subject” sequences. The original BLAST program used a protein “query ...

    • David Wheeler, Medha Bhagwat
    • 2007
  6. Aug 6, 2024 · The Basic Local Alignment Search Tool (BLAST) finds regions of similarity between sequences. The program compares nucleotide or protein sequences and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

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  8. Mar 17, 2021 · The BLAST algorithm looks at the problem of sequence database search, wherein we have a query, which is a new sequence, and a target, which is a set of many old sequences, and we are interested in knowing which (if any) of the target sequences is the query related to. One of the key ideas of BLAST is that it does not require the individual ...

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