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The Incucyte ® Live-Cell Analysis System automatically quantifies proliferation of PBMCs (yellow mask) activated with anti-CD3 antibody and IL-2 over a period of 144 hours. The full time course of PBMC proliferation is shown in the presence of anti-CD3 antibody and IL-2, anti-CD3 antibody alone, and in the absence of activators.
Sartorius AG is an international pharmaceutical and laboratory equipment supplier, covering the segments of Bioprocess Solutions and Lab Products & Services. In September 2021, Sartorius has been admitted to the DAX, Germany's largest (Blue chip) stock market index. [2] As a leading partner to the biopharmaceutical research and industry ...
- Molecular size: In general, large molecules are better antigens than small molecules. There is a direct correlation between the size of molecules and immunogenicity (Fig.
- Structural stability: The recognition of a molecule or part of a molecule as foreign is possible by the cells of the immune system due to its specific shape.
- Degradability: Easy degradation of an antigenic molecule is considered as an important factor with respect to their antigenicity. The cells of the immune system recognize small molecular fragments and soluble antigens.
- Foreignness: The first and foremost criteria for a molecule to function as an immunogen is that it must be or act as non-self to the host. The cells, whose function is to respond to antigen (antigen-sensitive cells) are selected in such a way that they do not usually respond to normal body components.
Incucyte ® live-cell analysis solutions include: Non-invasive, image-based measurements of cell growth based on area (confluence) or cell number (count) metrics, visually verified via images and movies. Selection of label-free or fluorescent assays depending on the specific scientific question being asked and the cell models studied.
Antigen-mediated antibody internalization plays an important role in several antibody-based therapeutics. There is a continued growing body of interest in the application of antibodies as therapeutic agents for delivery of treatments to sites or cells of interest with promise of increased efficacy and reduced side effect potential.
Dec 24, 2022 · Key Points. A homologous gene (or homolog) is a gene inherited in two species from a common ancestor. While homologous genes can be similar in sequence, similar sequences are not necessarily homologous. Orthologous are homologous genes where a gene diverges after a speciation event, but the gene and its main function are conserved.
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Bioacoustics is the study of sound in relation to animals. Bioacoustic monitoring has been transformed by the latest generation of super- sensitive digital audio recorders. Researchers at the British Trust for Ornithology (BTO), which is pioneering the tech in the UK, say that it’s like having “digital ears”.
