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  1. Oct 30, 2023 · The main function of the myocardium is to facilitate the contraction and relaxation of the heart walls in order to receive and pump the blood into the systemic circulation. In addition, the myocardial cells provide a scaffold for heart chambers and conduct electrical stimuli.

    • Pericardium

      Between the layers is the pericardial cavity, a potential...

  2. Jul 30, 2023 · Brain natriuretic peptide (BNP): a hormone secreted by the ventricular myocardium in response to ventricular wall stress (ie, pressure overload or volume expansion). The gold standard in diagnosing heart failure is the measurement of BNP levels, with an elevated level indicating heart failure.

    • 2023/07/30
  3. Their function is similar in many respects to neurons, although they are specialized muscle cells. Myocardial conduction cells initiate and propagate the action potential (the electrical impulse) that travels throughout the heart muscle and triggers the contractions that propel the blood.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
    • Dilated Cardiomyopathy
    • Hypertrophic Cardiomyopathy
    • Restrictive Cardiomyopathy
    • Arrhythmogenic Right Ventricular Dysplasia
    • Transthyretin Amyloid Cardiomyopathy

    Dilated cardiomyopathy causes the cardiac muscle tissue of the left ventricle to stretch and the heart’s chambers to dilate.

    Hypertrophic cardiomyopathy (HCM) is a genetic condition in which the cardiomyocytes are not arranged in a coordinated fashion and are instead disorganized. HCM can interrupt blood flow out of the ventricles, cause arrhythmias (abnormal electrical rhythms), or lead to congestive heart failure.

    Restrictive cardiomyopathy (RCM) refers to when the walls of the ventricles become stiff. When this happens, the ventricles cannot relax enough to fill with an adequate amount of blood.

    This rare form of cardiomyopathy causes fatty infiltration in cardiac muscle tissue in the right ventricle.

    Transthyretin amyloid cardiomyopathy (ATTR-CM) develops when amyloid proteins collect and form deposits in the walls of the left ventricle. The amyloid deposits cause the ventricle’s walls to stiffen, which prevents the ventricle from filling with blood and reduces its ability to pump blood out of the heart. This is a form of RCM.

  4. The brain controls the heart directly through the sympathetic and parasympathetic branches of the autonomic nervous system, which consists of multi-synaptic pathways from myocardial cells back to peripheral ganglionic neurons and further to central preganglionic and premotor neurons.

    • Alessandro Silvani, Giovanna Calandra-Buonaura, Roger A. L. Dampney, Pietro Cortelli
    • 2016
  5. Nov 7, 2024 · Myocardium. The myocardium is the thick, muscular middle layer of the heart wall responsible for the contractile function of the heart. It consists primarily of specialized cardiac muscle cells, known as cardiomyocytes, which have the unique ability to contract rhythmically and continuously throughout a person’s life.

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  7. The myocardial contractile cells constitute the bulk (99 percent) of the cells in the myocardium of the atria and ventricles. Myocardial contractile cells are autorhythmic, but they are primarily responsible for the strong, synchronized contractions necessary to pump blood through the body.

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