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      • An STPC develops during the first 12 weeks of the development of a fetus, or the first trimester. STPC has no known cause. The condition is common and doesn’t present any health problems for most people.
      www.healthline.com/health/simian-crease
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  2. In humans, a single transverse palmar crease is a single crease that extends across the palm of the hand, formed by the fusion of the two palmar creases.

  3. phalangeal joint. The genesis of the single upper palmar crease or of a transitional upper palmar crease pattern is not neces- sarily explained on the basis of a decreased sloping alignment of the third, fourth, and fifth metacarpal-phalangeal joints, as is evi- dent in Fig. 8. One possible factor which

    • Overview
    • Causes of a single transverse palmar crease
    • Disorders associated with a single transverse palmar crease
    • Complications associated with a single transverse palmar crease
    • The outlook for people with single transverse palmer crease

    Your hand’s palm has three large creases; the distal traverse palmar crease, the proximal transverse palmar crease, and the thenar transverse crease.

    •“Distal” means “away from the body.” The distal transverse palmar crease runs along the top of your palm. It begins close to your little finger and ends at the base of your middle or index finger, or between them.

    •“Proximal” means “toward the body.” The proximal transverse palmar crease is below the distal crease and somewhat parallel to it, running from one end of your hand to the other.

    •“Thenar” means “ball of the thumb.” The thenar transverse crease runs vertically around the base of your thumb.

    If you have a single transverse palmar crease (STPC), the distal and proximal creases combine to form one transverse palmar crease. The thenar transverse crease remains the same.

    An STPC used to be called a “simian crease,” but that term is no longer considered appropriate.

    An STPC develops during the first 12 weeks of the development of a fetus, or the first trimester. STPC has no known cause. The condition is common and doesn’t present any health problems for most people.

    Down syndrome

    This disorder occurs when you have an extra copy of chromosome 21. It causes intellectual disabilities, a characteristic facial appearance, and an increased chance for heart defects and digestive issues. According to the Centers for Disease Control and Prevention (CDC), Down syndrome is the most commonly diagnosed genetic condition in the United States.

    Fetal alcohol syndrome

    Fetal alcohol syndrome appears in children whose mothers drank alcohol during pregnancy. It may cause developmental delays and stunted growth. Children with this disorder may also have: •heart problems •nervous system problems •social problems •behavioral problems

    Aarskog syndrome

    Aarskog syndrome is an inherited genetic condition linked to your X chromosome. The syndrome affects your: •facial features •skeleton •muscle development

    An STPC doesn’t typically cause any complications. In one reported case, STPC was associated with fused carpal bones in the hand.

    Fused carpal bones can be related to many syndromes and can lead to:

    •hand pain

    •a greater likelihood of hand fractures

    STPC by itself doesn’t cause any health problems and is common among healthy people without any disorders. If you have STPC, your healthcare provider can use it to look for other physical characteristics of various conditions.

    If needed, they can order more tests to help them make a diagnosis.

    • Lydia Krause
  4. There are typically two creases in the palm, but in some people, only one crease is present. A single palmar crease occurs in about 1 out of 30 people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.

  5. Simian crease (SC), a single transverse crease that extends from across the palm of the hand. The presence of a single transverse palmar crease or the SC can be, but not always, a symptom associated with abnormal medical conditions.

  6. Jul 1, 2019 · The simian crease, aptly named for its resemblance to the palmar creases of non‐human simian primates, has received recognition clinically and anthropologically owing to its abnormal...

  7. A single transverse palmar crease, also known as a simian crease, is a condition where the typical three creases in the palm are replaced by a single line. This condition is often associated with certain genetic disorders, such as Down syndrome, and can also occur in individuals without any other health issues.

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