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  1. Oct 31, 2020 · The orbital apex is the area between the orbit and intracranial space that houses structures like the optic canal (OC), superior orbital fissure (SOF), and inferior orbital fissure (IOF), forming an opening to the orbit [2, 19, 30, 52, 92, 94, 108].

  2. Feb 8, 2018 · Orbital apex (OA) disorders include three groups of disorders: orbital apex syndrome (OAS), superior orbital fissure syndrome (SOFS) and cavernous sinus syndrome (CSS). OAS, also known as Jacod syndrome, is an uncommon disorder related to various etiologies involving the OA, including trauma, neoplastic, developmental, infectious, inflammatory as well as vascular causes.

    • Pradeep Goyal, Steven Lee, Nishant Gupta, Yogesh Kumar, Manisha Mangla, Kusum Hooda, Shuo Li, Rajiv ...
    • 10.1177/1971400917740361
    • 2018
    • Neuroradiol J. 2018 Apr; 31(2): 104-125.
    • Disease
    • Anatomy
    • Etiology
    • Pathophysiology
    • Signs/Symptoms
    • Differential Diagnosis

    Orbital apex syndrome (OAS) involves cranial neuropathies in association with optic nerve dysfunction. Orbital apex syndrome is symptomatically related to superior orbital fissure syndrome and cavernous sinus syndrome with similar etiologies. The distinction is the precise anatomic involvement of the disease process.

    The orbital apex is anatomically the posterior part of the orbit positioned at the craniofacial junction located where the four orbital walls converge. The orbital apex incorporates the optic canal and the superior orbital fissure. The optic canal transmits the optic nerve (surrounded by meninges) and the ophthalmic artery to the cranial fossa. The...

    Variety of etiologies and detailed history is important in narrowing the differential diagnosis. 1. Inflammatory 1.1. Sarcoidosis, SLE, Churg-Strauss syndrome, granulomatosis with polyangiitis , Tolosa Hunt Syndrome, Giant cell arteritis, Orbital inflammatory pseudotumor, thyroid orbitopathy, IgG4 related orbital myositis 2. Infectious – Most often...

    In the orbital apex syndrome dysfunction of the optic nerve (II), oculomotor nerve (III), trochlear nerve (IV), abducens nerve (VI), and/or the ophthalmic branch of the trigeminal nerve (V1) may occur. The exact etiology is protean but may be generally divided into inflammatory, infectious, neoplastic, traumatic, and iatrogenic causes.

    The most common initial manifestation of OAS is visual loss and ophthalmoplegia involving multiple cranial nerves

    Superior Orbital Fissure Syndrome (SOFS)
    Cavernous Sinus Syndrome (CSS)
  3. Jun 11, 2023 · Orbital apex syndrome (OAS), also called Jacod syndrome, is a complex neurological disorder characterized by a constellation of signs resulting from multiple cranial nerve involvement. [3] The typical clinical features are attributed to the involvement of the orbital apex by various neoplastic, vascular, infectious, or inflammatory conditions.

    • Arthi Mohankumar, Bharat Gurnani
    • 2023/06/11
  4. Oct 31, 2020 · The orbital apex is the narrowest part of the orbit, housing the link between the intracranial cavity and orbit. Knowledge of orbital apex anatomy is crucial to selecting a surgical approach and reducing the risk of complications. Our purpose is to summarize current knowledge on surgical anatomy and attempt to reach a consensus on definition of ...

    • Ӧ Engin, G F J P M Adriaensen, F W A Hoefnagels, P Saeed
    • 2021
  5. May 12, 2024 · the size of the muscles correlates with both the severity of disease and the risk of optic nerve compression 7. increase in retro-ocular orbital fat. The greater the extraocular muscle bulk (especially medial rectus bulk nearer to the apex) and the longer and narrower the bony orbit, the more crowded the orbital apex will become.

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  7. This pyramid transforms into to a 3-sided posterior apex, because the orbital floor ends at the posterior basin of the inferior orbital fissure. Bony openings (canals, grooves, fissures, foramina, notches) provide the pathways for the neurovascular structures linking the intraorbital structures inside the periorbital sac to the cranial cavity, ethmoid and skull base, infratemporal fossa, and face.

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