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  1. The pericardial layers and layers of the heart wall. The third layer of the heart wall is called the endocardium. It is a white sheet of endothelium (squamous epithelium) resting on a connective tissue layer. It is located on the inner myocardial surface and lines the heart chambers.

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    • Regina Bailey
    • Epicardium. Epicardium (epi-cardium) is the outer layer of the heart wall. It is also known as visceral pericardium as it forms the inner layer of the pericardium.
    • Myocardium. Myocardium (myo-cardium) is the middle layer of the heart wall. It is composed of cardiac muscle fibers, which enable heart contractions. The myocardium is the thickest layer of the heart wall, with its thickness varying in different parts of the heart.
    • Endocardium. Endocardium (endo-cardium) is the thin inner layer of the heart wall. This layer lines the inner heart chambers, covers heart valves, and is continuous with the endothelium of large blood vessels.
  2. Inside the pericardium, the surface features of the heart are visible, including the four chambers. There is a superficial leaf-like extension of each atrium near the superior surface of the heart, one on each side of the pulmonary trunk, called an auricle—a name that means “ear like”—because its shape resembles the external ear of a ...

  3. Sep 14, 2021 · The more delicate serous pericardium consists of two layers: the parietal pericardium, which is fused to the fibrous pericardium, and an inner visceral pericardium, or epicardium, which is fused to the heart and is part of the heart wall.

  4. Jan 4, 2024 · The innermost layer of the cardiac wall is known as the endocardium. It lines the cavities and valves of the heart. Structurally, the endocardium is comprised of loose connective tissue and simple squamous epithelial tissue – it is similar in its composition to the endothelium which lines the inside of blood vessels.

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  5. Nov 3, 2023 · The endocardium is the innermost layer of the heart. It lines the inner surfaces of the heart chambers, including the heart valves. The endocardium has two layers. The inner layer lines the heart chambers and is made of endothelial cells.

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  7. Oct 20, 2024 · The endocardium lines the chambers where the blood circulates and covers the heart valves. It is made of simple squamous epithelium called endothelium, which is continuous with the endothelial lining of the blood vessels (Figure \(\PageIndex{4}\)).