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The past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF).1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a background of an ageing and increasingly ...
Sep 13, 2019 · The clinical description of congestive heart failure has been recorded in the works of the ancient Greeks and Romans. Pathological analysis of an Egyptian dignitary who lived around 1479 BC and recovered from a plundered tomb in the Valley of the Queens revealed evidence of pulmonary edema—“likely due to heart failure,” according to Italian Egyptologist Ernesto Schiaparelli.
Sep 25, 2023 · Over time, stage B heart failure can progress to symptomatic heart failure (stages C and D). In a study of preclinical heart failure involving 413 people with stage B heart failure, 6% progressed to symptomatic heart failure over four years. A 2007 study found a 95.7% five-year survival rate for stage B heart failure.
Feb 28, 2020 · Abstract. Heart failure is an epidemic disease which affects about 1% to 2% of the population worldwide. Both, the etiology and phenotype of heart failure differ largely. Following a cardiac injury (e.g., myocardial infarction, increased preload or afterload) cellular, structural and neurohumoral modulations occur that affect the phenotype ...
- Robert H. G. Schwinger
- 10.21037/cdt-20-302
- 2021
- 2021/02
Apr 1, 2022 · Aim: The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure” replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the “2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure.” The 2022 guideline is intended to provide patient-centric recommendations for clinicians to prevent, diagnose, and manage ...
Apr 10, 2024 · Epidemiology. The Global Burden of Disease Study estimated that 57 million people were living with heart failure in 2019.3 4 Although this number has been increasing in countries with aging populations, the age standardized rate has fallen from 7.7 per 1000 in 2010 to 7.1 per 1000 in 2019.3 4 The change over time in the age adjusted prevalence from 2009 to 2019 (an average 0.3% decline per ...
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May 1, 2008 · The present article describes how our understanding of heart failure has evolved over the past 2500 years. Having been active in this area since the 1950s and having shared many reminiscences with my father, Louis N. Katz, who played an active role in academic cardiology between the 1920s and 1970s, I have included several personal insights about progress since the beginning of the 20th century.
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