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Nov 4, 2021 · Although ALP exists throughout your body, the two main sources of ALP in your blood are your liver and bones. High levels of ALP may indicate liver disease or certain bone disorders, but an ALP test alone cannot diagnose a condition.
Aug 20, 2020 · ALP is found in decreasing concentrations in various organs such as the placenta, ileal mucosa, kidney, bone, and liver. Over 80% of the ALP in serum originates from the liver and bone, with minor contributions from the intestine.
- 2023/10/29
In humans, it is found in many forms depending on its origin within the body – it plays an integral role in metabolism within the liver and development within the skeleton. Due to its widespread prevalence in these areas, its concentration in the bloodstream is used by diagnosticians as a biomarker in helping determine diagnoses such as ...
Alkaline phosphatase (ALP; E.C.3.I.3.1.) is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. Alkaline phosphatase is divided into four isozymes depending upon the site of tissue expression that are Intestinal ALP, Placental ALP, Germ cell ALP and tissue nonspecific alkaline ...
Sep 11, 2024 · Alkaline phosphatase (ALP) is an enzyme found in several organs in the body, including the liver, bones, kidneys, and digestive system. This enzyme plays an important role in breaking down proteins, aiding in the proper function of various body systems.
Nov 1, 2023 · Alkaline phosphatase (ALP) is mainly found in your liver and bones, but small amounts are also in your digestive system, kidneys, and the placenta during pregnancy.
Aug 3, 2024 · However, its highest concentrations are found in the liver, bones, kidneys, and intestines as well as the bile ducts (which drain bile from the liver) and gallbladder (which stores bile). Certain diseases or conditions can impair ALP synthesis and lead to a drop in blood concentration.
