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James Patrick Allison (born August 7, 1948) [ 4 ] is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center in Houston, Texas. [ 5 ]
James P. Allison (born August 7, 1948, Alice, Texas, U.S.) is an American immunologist who contributed to the discovery of mechanisms underlying T-cell activation and who was a pioneer in the development of immune checkpoint therapy for cancer. For his discoveries, Allison shared the 2018 Nobel Prize for Physiology or Medicine with Japanese ...
- Kara Rogers
- Early Life, South Texas
- The University of Texas at Austin: Undergraduate and Graduate Training
- Scripps Clinic and Research Foundation: 1974–77
- The University of California, Berkeley: 1984–2004
- Memorial Sloan-Kettering Cancer Center: 2004–2012
- University of Texas MD Anderson Cancer Center: 2012–Present
I was born in 1948 in Alice, a small farming and oil town in the brush country of the Rio Grande Valley in South Texas. Those early years in Alice shaped who I would later become. Being in Texas, the whole town, including my two older brothers, was obsessed with football. But, I learned from a young age that being crushed under a pile of big sweaty...
I enrolled at UT Austin in the summer session immediately after high school graduation. Due to my summers in Austin, I never thought of going anywhere else. In accordance with my father’s hopes, I began as a premed student. However, I became dissatisfied with the rote memorization required in some of the pre-med courses. At the beginning of my seco...
Professors Mandy and Kitto helped me get a post-doctoral appointment in Ralph Reisfeld’s laboratory at Scripps Clinic in La Jolla, California. I felt that this was a great choice because Scripps was a hotbed of research in immunology, and because Reisfeld had recently reported the isolation and initial characterization of human histocompatibility (...
UC Berkeley is a marvelous place, teeming with bright, inventive people seeking knowledge. My time at UC Berkeley was notable for my interactions with many wonderful colleagues and students. It was a time of discovery, collegiality, long days working in the lab, and long nights partying with everyone in the lab. Max Krummel described it best by say...
I arrived in Manhattan during the summer of 2004 with most of my laboratory intact. Over the next 8 years, I did my best to help Thomas Kelly hire a cadre of the best immunologists that we could, and I feel that we succeeded in building a truly spectacular group of basic immunologists involved in a variety of studies relevant to the cancer problem....
At MSKCC, my lab had continued exploring ways in which to improve anti-tumor responses with anti-CTLA-4 treatment. We performed many experiments including combinations with chemotherapy, radiation therapy, cryoablation and with other immune checkpoint agents. After anti-CTLA-4 was shown to have some clinical success in the early clinical trials, ma...
Apr 1, 2024 · James Allison, Ph.D., is co-leader of the Immunotherapy Moon Shot platform at MD Anderson Cancer Center. He was recently named one of TIME’s 100 most influential people for his groundbreaking immunotherapy research. Learn more about Dr. Allison.
James P. Allison The Nobel Prize in Physiology or Medicine 2018. Born: 7 August 1948, Alice, TX, USA. Affiliation at the time of the award: Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA; University of Texas MD Anderson Cancer Center, Houston, TX, USA. Prize motivation: “for their discovery of cancer therapy by inhibition ...
Oct 1, 2018 · James P. Allison was born 1948 in Alice, Texas, USA. He received his PhD in 1973 at the University of Texas, Austin. From 1974-1977 he was a postdoctoral fellow at the Scripps Clinic and Research Foundation, La Jolla, California.
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Oct 1, 2018 · Editor's note: This story was updated at 2:45 p.m. to include more information. James P. Allison and Tasuku Honjo will be awarded the 2018 Nobel Prize in Physiology or Medicine for discoveries ...
