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Oct 22, 2018 · James Allison looks like a cross between Jerry Garcia and Ben Franklin, and he’s a bit of both, an iconoclastic scientist and musician known for good times and great achievements. He also doesn ...
Aug 14, 2019 · Such is the story of James P. Allison, PhD, the Texas immunologist who conceived during graduate school that T cells could have a role in fighting cancer—and then chased this idea to develop ...
- Mary Caffrey
Jan 27, 2023 · Allison, a Nobel laureate whose research led to the discovery of the T-cell antigen receptor and the anti CTLA-4 antibody ipilimumab, and director of James P. Allison Institute, Regental Chair of Immunology, and vice president of immunobiology at MD Anderson Cancer Center, said to The Cancer Letter. Allison is also the Olga Keith Wiess Distinguished University Chair for Cancer Research and ...
James Patrick Allison (born August 7, 1948) [ 4 ] is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center in Houston, Texas. [ 5 ]
- Early Life, South Texas
- The University of Texas at Austin: Undergraduate and Graduate Training
- Scripps Clinic and Research Foundation: 1974–77
- The University of California, Berkeley: 1984–2004
- Memorial Sloan-Kettering Cancer Center: 2004–2012
- University of Texas MD Anderson Cancer Center: 2012–Present
I was born in 1948 in Alice, a small farming and oil town in the brush country of the Rio Grande Valley in South Texas. Those early years in Alice shaped who I would later become. Being in Texas, the whole town, including my two older brothers, was obsessed with football. But, I learned from a young age that being crushed under a pile of big sweaty...
I enrolled at UT Austin in the summer session immediately after high school graduation. Due to my summers in Austin, I never thought of going anywhere else. In accordance with my father’s hopes, I began as a premed student. However, I became dissatisfied with the rote memorization required in some of the pre-med courses. At the beginning of my seco...
Professors Mandy and Kitto helped me get a post-doctoral appointment in Ralph Reisfeld’s laboratory at Scripps Clinic in La Jolla, California. I felt that this was a great choice because Scripps was a hotbed of research in immunology, and because Reisfeld had recently reported the isolation and initial characterization of human histocompatibility (...
UC Berkeley is a marvelous place, teeming with bright, inventive people seeking knowledge. My time at UC Berkeley was notable for my interactions with many wonderful colleagues and students. It was a time of discovery, collegiality, long days working in the lab, and long nights partying with everyone in the lab. Max Krummel described it best by say...
I arrived in Manhattan during the summer of 2004 with most of my laboratory intact. Over the next 8 years, I did my best to help Thomas Kelly hire a cadre of the best immunologists that we could, and I feel that we succeeded in building a truly spectacular group of basic immunologists involved in a variety of studies relevant to the cancer problem....
At MSKCC, my lab had continued exploring ways in which to improve anti-tumor responses with anti-CTLA-4 treatment. We performed many experiments including combinations with chemotherapy, radiation therapy, cryoablation and with other immune checkpoint agents. After anti-CTLA-4 was shown to have some clinical success in the early clinical trials, ma...
Oct 1, 2018 · Immunologist James P. Allison today shared the 2018 Nobel Prize in Physiology or Medicine for groundbreaking work he conducted on cancer immunotherapy at the University of California, Berkeley, during his 20 years as director of the campus’s Cancer Research Laboratory. Allison, who is now at the M.D. Anderson Cancer Center in Houston, Texas ...
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James P. Allison (born August 7, 1948, Alice, Texas, U.S.) is an American immunologist who contributed to the discovery of mechanisms underlying T-cell activation and who was a pioneer in the development of immune checkpoint therapy for cancer. For his discoveries, Allison shared the 2018 Nobel Prize for Physiology or Medicine with Japanese ...
