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    • Helps break down food

      • Parietal cells are present in the gastric pits that mainly occur in the upper part of the stomach, or the fundus. They secrete hydrochloric acid, which helps break down food. Hydrochloric acid also kills bacteria and other microorganisms that may be present in food.
      www.medicalnewstoday.com/articles/cells-of-the-stomach
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  2. Oct 17, 2022 · Parietal cells secrete hydrochloric acid that helps break down food and intrinsic factor that aids in the absorption of vitamin B12. Chief cells secrete enzymes that support digestion.

  3. Apr 1, 2020 · Hydrochloric acid secreted from gastric parietal cells generates the strongly acidic environment of the gastric lumen (pH <2) (305), which kills food-derived bacteria, facilitates food digestion, and promotes absorption of minerals including phosphate, calcium, and iron.

    • Amy C. Engevik, Izumi Kaji, James R. Goldenring
    • 2020
  4. The Breakdown of Protein. One major role of HCl in the stomach is to help break down protein. Your stomach lining contains specialized cells, called parietal cells, that release stomach acid in the presence of food. Other cells in the lining of your stomach, called chief cells, secrete other important substances, one of which is called pepsinogen.

    • Lindsay Boyers
  5. These relatively large cells produce both hydrochloric acid (HCl) and intrinsic factor. HCl is responsible for the high acidity (pH 1.5 to 3.5) of the stomach contents and is needed to activate the protein-digesting enzyme, pepsin.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
  6. Jul 17, 2023 · Hydrochloric acid (HCl), the main constituent of gastric acid, is secreted by parietal cells. The hydrogen (H) and chloride (Cl) components of HCl are secreted separately by hydrogen/potassium ATPase pumps and chloride channels in the stomach.

    • Mark Hsu, Anthony O. Safadi, Forshing Lui
    • 2023/07/17
  7. When stimulated, parietal cells secrete HCl at a concentration of roughly 160 mM (equivalent to a pH of 0.8). The acid is secreted into large cannaliculi, deep invaginations of the plasma membrane which are continuous with the lumen of the stomach.

  8. Jul 17, 2023 · Hydrochloric Acid Production. HCl is produced by the parietal cells of the stomach. To begin with, water (H 2 O) and carbon dioxide (CO 2) combine within the parietal cell cytoplasm to produce carbonic acid (H 2 CO 3), which is catalysed by carbonic anhydrase.

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