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  1. Aug 12, 2020 · Sjögren’s syndrome (SS) is a complex and heterogeneous disorder that follows a strong trend of female predilection observed in many autoimmune diseases, ranking second after autoimmune thyroiditis [1]. The clinical spectrum of SS extends beyond the exocrine glands, including many extraglandular manifestations, either periepithelial ...

    • Loukas Chatzis, Vasileios C Pezoulas, Francesco Ferro, Saviana Gandolfo, Valentina Donati, Marco Bin...
    • 10.3390/jcm9082620
    • 2020
    • J Clin Med. 2020 Aug; 9(8): 2620.
  2. May 17, 2022 · Results showed that Sjögren’s patients had a 2.17-times higher risk of developing cancer than the general population. This risk was even more substantial in patients from Europe or Asia. The risk also was higher among patients who were diagnosed with Sjögren’s using the American-European Consensus Group diagnostic criteria, from the Johns ...

    • Science Writer
  3. Sjögren's is a chronic autoimmune disease that is likely more prevalent in men than currently appreciated. At present, one out of every ten diagnosed patients is male, but that number is expected to grow as awareness is raised.

    • 10701 Parkridge Blvd. Suite 170, Reston, 20191, VA
  4. Progression of Sjögren Syndrome. Sjögren Syndrome is a chronic disease that progresses very slowly over time. Because of this, there may be a period of up to 10 years between the onset of symptoms and the diagnosis of the disease. As these symptoms usually appear in middle-aged women, they can be seen as normal ageing or menopausal symptoms ...

    • Manuel Ramos Casals
  5. Apr 17, 2017 · SIRs for specific cancers were 36.17 for multiple myeloma and immunoproliferative diseases, 19.41 for Hodgkin lymphoma, 6.04 for other non-Hodgkin lymphomas, 5.17 for thyroid cancer, 4.81 for cancers of the lip and oral cavity, and 2.53 for stomach cancer. Conclusions: One third of cancers developed by patients with primary SjS are B-cell ...

    • Pilar Brito-Zerón, Belchin Kostov, Guadalupe Fraile, Daniel Caravia-Durán, Brenda Maure, Francisco-J...
    • 2017
  6. Aug 25, 2023 · Sjögren’s disease is difficult to diagnose! Nearly half of all patients are considered especially difficult to diagnose even though symptoms clearly point to Sjögren’s. Currently, we have only two options available to healthcare providers (HCPs) to clearly diagnose Sjögren’s: testing positive on a lip biopsy and testing positive for a prominent autoantibody associated with Sjögren ...

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  8. A: In the autoimmune attack that causes Sjögren’s, disease-fighting white blood cells called lymphocytes target the glands that produce moisture – primarily the lacrimal (tear) and salivary (saliva) glands. Although no one knows exactly how damage occurs, damaged glands can no longer produce tears and saliva, and eye and mouth dryness result.

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