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Oct 20, 2021 · CNS fibroblasts contribute in important ways to CNS development and disease pathology, progression and recovery. Their role in contributing to CNS fibrosis makes them important drug targets for the treatment of neurological diseases and conditions.
- Cayce E. Dorrier, Hannah E. Jones, Lucija Pintarić, Julie A. Siegenthaler, Richard Daneman
- 10.1038/s41583-021-00525-w
- 2021
- Nat Rev Neurosci. 2022; 23(1): 23-34.
Oct 20, 2021 · Recent transcriptomic, histological and functional studies have begun to shine light on the fibroblasts present in the meninges, choroid plexus and perivascular spaces of the brain and spinal...
- Cayce E. Dorrier, Hannah E. Jones, Lucija Pintarić, Julie A. Siegenthaler, Richard Daneman
- 2021
May 4, 2021 · In this review, we first introduce the anatomic location and molecular markers of CNS fibroblast-like cells. Next, the functions of fibroblast-like cells in CNS development and neurological disorders, including stroke, CNS traumatic injuries, and other neurological diseases, are discussed.
- Lingling Xu, Yao Yao
- 2021
First, the bones of the skull enclose and house the brain. Underneath the skeletal structures, the brain is protected by membranes made by connective tissue, called meninges, that surround, support, stabilize and partition the nervous tissue (Figure 12.2.1 12.2. 1).
How does bone affect the brain? The skeleton, X-rayed by a beam of brain cues is not a passive target, but rather an active participant, sending information back to the brain and other organs.
Jul 24, 2023 · The dura mater is very important to the clinician because it is a barrier to the internal environment of the brain, and surgically, the neurosurgeon and clinician who interpret imaging should understand its anatomy.
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When a tissue is injured, the fibroblasts nearby proliferate, migrate into the wound, and produce large amounts of collagenous matrix, which helps to isolate and repair the damaged tissue.
