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    • Image courtesy of sharedocnow.blogspot.com

      sharedocnow.blogspot.com

      • The right and left cerebral hemispheres are connected by a thick fiber bundle (collection of axons) called the corpus callosum. This allows information to pass from one side to the other side of the brain.
      openstax.org/books/introduction-behavioral-neuroscience/pages/1-4-the-brain-structure-and-function
  1. Oct 20, 2021 · Recent work has revealed that fibroblasts play crucial roles in fibrotic scar formation in the CNS after injury and inflammation, which have also been attributed to other perivascular cell types such as pericytes and vascular smooth muscle cells.

    • Cayce E. Dorrier, Hannah E. Jones, Lucija Pintarić, Julie A. Siegenthaler, Richard Daneman
    • 10.1038/s41583-021-00525-w
    • 2021
    • Nat Rev Neurosci. 2022; 23(1): 23-34.
  2. Underneath the skeletal structures, the brain is protected by membranes made by connective tissue, called meninges, that surround, support, stabilize and partition the nervous tissue (Figure \(\PageIndex{1}\)). In addition, the brain has a privileged blood supply, as suggested by the blood-brain barrier.

  3. Oct 20, 2021 · Perivascular spaces in the CNS are home to various cell types that have important roles in communicating between the periphery and the brain and spinal cord parenchyma.

    • Cayce E. Dorrier, Hannah E. Jones, Lucija Pintarić, Julie A. Siegenthaler, Richard Daneman
    • 2021
  4. May 4, 2021 · In this review, we first introduce the anatomic location and molecular markers of CNS fibroblast-like cells. Next, the functions of fibroblast-like cells in CNS development and neurological disorders, including stroke, CNS traumatic injuries, and other neurological diseases, are discussed.

    • Lingling Xu, Yao Yao
    • 2021
  5. Mar 1, 2024 · Based on their distinct anatomical locations in the meninges, perivascular space, and choroid plexus, as well as their molecular diversity, important roles for fibroblasts in the CNS have been proposed.

  6. Aug 14, 2020 · Fibrotic scarring, also called mesenchymal scarring, represents the central core of the CNS acute lesions and it mainly consists of endothelial cells and inflammatory immune cells, including monocyte-derived macrophages, stromal fibroblasts, and ECM deposits.

  7. The CNS is the processing centre of the body and consists of the brain and the spinal cord. Both of these are protected by three layers of membranes known as meninges. For further protection, the brain is encased within the hard bones of the skull, while the spinal cord is protected with the bony vertebrae of our backbones.