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  1. Jul 17, 2021 · Certain alternatives allow for a more environmentally friendly use of oxygen therapy. Medical oxygen can be produced thanks to oxygen generators at the heart of hospitals installed using PSA (Pressure Swing Adsorption) technology.

    • Laure Bonnet, Albertine Carle, Jane Muret
    • 2021
  2. Application of oxygen therapies and respiratory support measures is challenging because COVID-19 differs from other viral respiratory infections (such as influenza and seasonal endemic coronavirus). Given the lack of knowledge supported by scientific evidence, medical treatment has been administered based on expert opinions.

    • Patient Comfort Increases with High Flow Oxygen Therapy2
    • High Flow O2 Therapy Provides Interventions Obtainable Outside The ICU Setting
    • High Flow O2 Therapy May Reduce Intubation Rates in Patients with Covid-195
    • Additional Benefits of High Flow Oxygen Therapy
    • References

    It’s been well established that face masks with a reservoir bag, while a first line therapy, provide little when it comes to patient comfort. The air is dry, and the masks prevent patients from doing many basic functions. Wearing a face mask hinders the patient from communicating, drinking, or eating without removing the mask. Face masks can also c...

    A major challenge for healthcare providers and organizations caring for patients with COVID-19 is access to beds and rooms. ICUs and step-down units were often beyond capacity, highlighting the need for interventions that can be done safely outside of an ICU setting. High flow oxygen therapy has proven to be one of these vital interventions that ca...

    The use of high flow oxygen therapy (HFNO) has been evaluated in several studies specifically focused on patients with COVID-19. A retrospective study out of France found patients who undergo HFNO were less likely to need mechanical ventilation (56% of HFNO group versus 71% in non-HFNO group).5 The mortality rate of these patients with COVID-19 res...

    High flow O2 therapy is not only a practical intervention for patients with COVID-19 related hypoxemic respiratory failure, but it also provides additional physiological benefits. These benefits include: 2 1. Alveolar recruitment 2. Improved perfusion matching 3. Reducing airway resistance 4. Reduced respiratory effort 5. Decreased oxygen dilution ...

    Ashraf-Kashani, N et al. (2017) High-flow nasal oxygen therapy. BJA Education, 17 (2):57–62.
    Calligaro G. et al. (2020) The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: a multi-center prospective observational study. E Clinical Medicine...
    Lyons, C & Callaghan, M. (2020). The use of high-flow nasal oxygen in COVID-19. Anaesthesia. 75(7): 843-847.
    Jackson, J et al (2021). Implementation of high-flow nasal cannula therapy outside the intensive care setting. Respiratory Care. 66(3): 357-365.
  3. Feb 2, 2024 · The results of our network meta-analysis suggest that noninvasive ventilation, high-flow nasal oxygen, and conventional oxygen therapy are comparable in terms of treatment failure and mortality outcomes in COVID-19-associated acute respiratory failure.

    • 10.1016/j.bja.2023.12.022
    • 2024/05
    • Br J Anaesth. 2024 May; 132(5): 936-944.
  4. As the COVID-19 pandemic evolves, new effective treatment options are essential for reducing morbidity and mortality as well as the strain placed on the healthcare system. Since publication of our initial review on hyperbaric oxygen treatment (HBOT) ...

  5. Rationale In patients with COVID-19 pneumonia and mild hypoxaemia, the clinical benefit of high-flow nasal oxygen (HFNO) remains unclear. We aimed to examine whether HFNO compared with conventional oxygen therapy (COT) could prevent escalation of respiratory support in this patient population.

  6. Apr 17, 2023 · In this review, we summarize the classical oxygen therapies and highlight several potential micro and nanotechnological strategies to be employed as oxygen therapy alternatives in COVID-19 patients.