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1. pubmed.ncbi.nlm.nih.gov › 34617510Modulation of fracture healing by the transient accumulation ...

   pubmed.ncbi.nlm.nih.gov › 34617510

   Oct 7, 2021 · Our findings thus demonstrate that senescent cells accumulate transiently in the murine fracture callus and, in contrast to the skin, their clearance does not impair but rather improves fracture healing. Keywords: bone; callus; fracture; medicine; mouse. © 2021, Saul et al.

   • Author: Dominik Saul, Dominik Saul, David G Monroe, Jennifer L Rowsey, Robyn Laura Kosinsky, Stephanie J Vos...

   • Publish Year: 2021

2. www.nature.com › articles › s41586/021/03362-0NASH limits anti-tumour surveillance in immunotherapy-treated ...

   www.nature.com › articles › s41586/021/03362-0

   Mar 24, 2021 · Preventive anti-PD1 treatment was strongly associated with the pro-tumorigenic immunosuppressive ICF signature (for example, Ifng, Tnf, Stat3, Tgfb1), capturing the traits of T cell exhaustion...

   • Author: Dominik Pfister, Dominik Pfister, Nicolás Gonzalo Núñez, Roser Pinyol, Olivier Govaere, Matthias Pin...

   • Publish Year: 2021

3. pubmed.ncbi.nlm.nih.gov › 34326518The immunological and metabolic landscape in primary and ...

   pubmed.ncbi.nlm.nih.gov › 34326518

   In this Review, we discuss how the hepatic microenvironment adapts to pathologies characterized by chronic inflammation and metabolic alterations. We illustrate how these immunological or metabolic changes alter immunosurveillance and thus hinder or promote the development of primary liver cancer.

   • Author: Xin Li, Pierluigi Ramadori, Dominik Pfister, Marco Seehawer, Lars Zender, Lars Zender, Mathias Heike...

   • Publish Year: 2021

4. www.sciencedirect.com › science › articleThe examination of Fama-French Model during the Covid-19

   www.sciencedirect.com › science › article

   Jul 1, 2021 · This paper evaluates the performance of Fama-French models on US stock markets during the selected events by studying the R2 of the models. We find that the influence of Dotcom bubble to the R2 of growth model is statistically significant. The R2 of growth portfolios decreases rapidly during the Financial crisis of 2008.

   • Author: Dominik Horváth, Yung-Lin Wang

   • Publish Year: 2021

5. www.sciencedirect.com › science › articleImmunology of SARS-CoV-2 infections and vaccines - ScienceDirect

   www.sciencedirect.com › science › article

   Jan 1, 2021 · The efficacy of the AstraZeneca vaccine drops precipitously against the beta variant (Madhi et al., 2021), though in all likelihood there is still some protection against severe disease against this and other variants such as delta (Public Library—PHE National—Knowledge Hub, n.d.).

   • Author: Dominik Schenten, Deepta Bhattacharya

   • Publish Year: 2021

6. www.nature.com › articles › s42005/021/00703-3Persistent fluid flows defined by active matter boundaries

   www.nature.com › articles › s42005/021/00703-3

   Aug 27, 2021 · Abstract. Biological systems control ambient fluids through the self-organization of active protein structures, including flagella, cilia, and cytoskeletal networks.

7. People also ask

   Does cdkn2aluc induce transient senescent cell accumulation during callus formation?

   • Then, using a genetic mouse model ( Cdkn2aLUC) containing a Cdkn2aInk4a -driven luciferase reporter, we demonstrated transient in vivo senescent cell accumulation during callus formation.

   Modulation of fracture healing by the transient accumulation of senesce…

   pubmed.ncbi.nlm.nih.gov/34617510/

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   Do anti-pd1-treated Nash mice have non-proliferative T cells?

   • CD8 + PD1 + T cells were non-proliferative in anti-PD1-treated NASH mice; this result was supported by in vitro experiments, in which anti-PD1 treatment led to increased T cell numbers in the absence of proliferation (Extended Data Fig. 6l, m).

   NASH limits anti-tumour surveillance in immunotherapy-treated HCC

   www.nature.com/articles/s41586-021-03362-0

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   How does anti-PD1 immunotherapy affect PD1 expression in Nash mice?

   • Thus, upon anti-PD1 immunotherapy in NASH mice, CD8 + PD1 + T cells accumulated to high numbers in the liver, revealing a resident-like T cell character with increased expression of CD44, CXCR6, EOMES and TOX and low levels of CD244 expression, but lacking expression of TCF1/TCF7, CD62L, TBET, and CD127 (Extended Data Fig. 6p–u).

   NASH limits anti-tumour surveillance in immunotherapy-treated HCC

   www.nature.com/articles/s41586-021-03362-0

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   Can optically induce microtubule and flow-field dynamics?

   • We developed an experimental platform 19 that allows us to optically induce and track both microtubule and flow-field dynamics (Supplementary Methods 2 ). Our experimental system (Fig. 1 b) uses a conventional fluorescence microscope and a digital light projector to control sample illumination.

   Persistent fluid flows defined by active matter boundaries

   www.nature.com/articles/s42005-021-00703-3

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8. www.thelancet.com › journals › langloEstimates of the global burden of cervical cancer associated ...

   www.thelancet.com › journals › langlo

   Nov 16, 2020 · We systematically searched five databases (PubMed, Embase, Global Health [CABI.org], Web of Science, and Global Index Medicus) to identify studies analysing the association between HIV infection and cervical cancer. The detailed search strategy can be found in the appendix (pp 3–6).