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  2. May 16, 2024 · The cast of Grey's Anatomy Season 1 is iconic, but many of them are no longer on the show. Find out what they've been up to since they left. The show turned its stars into household names.

    • Ellen Pompeo as Meredith Grey. The titular character of Grey's Anatomy, audiences were introduced to Meredith Grey on the morning of her first day as an intern at Seattle Grace hospital.
    • James Pickens Jr. as Richard Webber. Richard Webber was introduced on the first episode of the series. As the former Chief of Surgery, Richard immediately recognized Meredith's talent and lineage, having worked with her mother, Ellis Grey (Kate Burton).
    • Chandra Wilson as Miranda Bailey. Miranda Bailey was introduced to viewers as "The Nazi" for her stern demeanor and refusal to take any nonsense on the series premiere.
    • Justin Chambers as Alex Karev. Justin Chambers portrayed Alex Karev, the cocky, overconfident intern who had the nerve to call Meredith a nurse on the first episode.
  3. Jan 10, 2020 · After over a decade, here's what the original cast of "Grey's Anatomy" is up to now.

    • Elana Rubin
    • Henry Blodget
    • Sandra OH
    • Katherine Heigl
    • T. R. Knight
    • Isaiah Washington
    • Patrick Dempsey
    • Kate Burton
    • Kate Walsh
    • Sarah Utterback
    • Eric Dane
    • Steven W. Bailey

    Sandra Oh portrayed Cristina Yang for the first 10 seasons. At the time she was leaving the show, her character had grown from a surgical intern to the Director of Cardiothoracic Surgery at the Klausman Institute for Medical Research. Oh has had a great run outside the show. She currently has a main role in the spy drama Killing Evewhere she portra...

    Heigl starred as surgical oncologist Izzie Stevens for the first 6 seasons of the medical drama. The role won her an Emmy for "Outstanding Supporting Actress in a Drama Series." She recently returned to the show courtesy of a guest appearance in Season 16's "Leave a Light On." After her departure, Heigl starred in a number of romcoms. She then went...

    Knight was the trauma surgeon George O'Malley until Season 5. The actor gave a couple of reasons for leaving the show that included failure to agree with showrunner Rhimes and his character's lack of ample screen-time. RELATED: Grey's Anatomy: The Main Characters, Ranked By Work Ethic Life hasn't been bad for Knight away from Grey's Anatomy. He cur...

    Washington's character Preston Burke will always be remembered as the man who left Cristina at the altar. Even though the cardiothoracic surgeon redeemed himself, it's impossible to forget the incident. Washington left the show after the third season. The actor has had a couple of key roles after leaving Grey's Anatomy. His most notable one is that...

    Dempsey's character Derek Shepherd aka McDreamy had "Gifted Hands." He was the only doctor who would gladly take on the most difficult of cases. His romance with Meredithwas also something to behold. In Season 17, he appeared in Meredith's visions after she was diagnosed with Covid-19. Except for the financial thriller series Devils, Dempsey hasn't...

    Burton is best remembered for playing Meredith's mother and world-famous surgeon Ellis Grey. She appeared on the show for the first three seasons then left once her character succumbed to Alzheimer's. RELATED: Grey's Anatomy: 10 Hidden Details You Missed About Grey Sloan Memorial Hospital The actress appeared in the other popular Shondaland show Sc...

    For the first eight seasons, Walsh had a recurring role as Addison Montgomery, the double board-certified OB/GYN, who specialized in fetal surgery. She also portrayed the same character in the spinoff Private Practice. After leaving the show, Walsh went on to star in the Netflix hit series 13 Reasons Why, as the parent of a child who committed suic...

    Sarah Utterback played Olivia Harper, a nurse at Seattle Grace who had an affair with both Alex and George. She was fired after it was announced that Seattle Grace was merging with Mercy West Medical Center. Utterback returned in Season 14's "Bad Reputation" in a guest capacity. The actress hasn't done much after leaving Grey's Anatomy. Her last cr...

    Dane is best remembered for portraying the medical drama's resident playboy Mark Sloan aka McSteamy. Sadly, the fan-favorite character succumbed to injuries he suffered during the infamous plane crash. RELATED: 10 Biggest Celebrity Guest Stars To Appear On Grey's Anatomy At the moment, Dane has a main role in the HBO teen drama Euphoria where he pl...

    Bailey was one of the actors who got to portray two different characters in Grey's Anatomy. First, he appeared as the anesthesiologist Jeremy in Season 1 before returning in Season 2 as Joe, the owner of Emerald City Bar aka Joe's. The actor left the show after Season 7, though the bar continues to operate. The actor has mostly landed guest roles i...

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    • Denny Duquette (Jeffrey Dean Morgan) Active: Season 1-2. Who Was Denny Duquette? Denny Duquette was one of the best characters on the show, you hear me? Denny was a dying patient at Seattle Grace Hospital (back when it was called Seattle Grace Hospital*)
    • Dr. Preston Burke (Isaiah Washington) Active: Seasons 1-3. Status: Dead to Shonda Rhimes. Who Was Dr. Preston Burke? Dr. Preston Burke was a Grey’s Anatomy O.G!
    • Dr. Addison Montgomery (Kate Walsh) Active: Seasons 1-8 and 18-19. Who Was Dr. Addison Montgomery? She’s Dr. Derek Shepherd’s ex-wife!!! She’s also a world-renowned OBGYN but who really cares, we all know we watch Grey’s for the love triangles.
    • Dr. George O’Malley (T.R. Knight) Active: Seasons 1-6. Who Was George O’Malley’? Okay, Grey’s Anatomy fans really were obsessed with George even though personally I never understood it…
  4. Jan 10, 2020 · Along with Meredith/Ellen, the only other O.G. cast members now remaining are Chandra Wilson, who plays Dr. Miranda Bailey, and James Pickens Jr., who plays Dr. Richard Webber. They’ve both...

  5. Jun 30, 2024 · Justin Chambers, Katherine Heigl and Patrick Dempsey are just some of the stars who’ve left ‘Grey’s Anatomy — see what they’re up to now.

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