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1. • • Now, a pilot study led by Stanford Medicine researchers has found that a ketogenic diet not only restores metabolic health in these patients as they continue their medications, but it further improves their psychiatric conditions.
     med.stanford.edu/news/all-news/2024/04/keto-diet-mental-illness.html

     Pilot study shows ketogenic diet improves severe mental illness

2. www.frontiersin.org › journals › psychiatrySleep, mood disorders, and the ketogenic diet: potential ...

   www.frontiersin.org › journals › psychiatry

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   Feb 13, 2024 · Recent clinical trials using the ketogenic diet suggest positive improvement in symptoms for bipolar disorder and schizophrenia as well. The improvement in psychiatric symptoms from the ketogenic diet is thought to be linked, in part, to restoration of mitochondrial function.

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     How the Ketogenic Diet Helps Schizophrenia

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     What is Schizoaffective Disorder- Is It Worse Than Bipolar Disorder?

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     Ketogenic diet as treatment for epilepsy

     Mar 4, 2018

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4. www.chrispalmermd.com › ketogenic-diet-bipolarCan a ketogenic diet successfully treat Bipolar Disorder?

   www.chrispalmermd.com › ketogenic-diet-bipolar

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   • The Epilepsy Connection
   • Energy Metabolism in Brain Cells
   • Is There Evidence That The Ketogenic Diet Can Work in Bipolar Disorder?
   • So… Should People Just Try This Diet on Their own?
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   Many treatments that are approved for the treatment of epilepsy also work for bipolar disorder and other psychiatric disorders, including medications like Depakote (valproic acid), Tegretol (carbamazepine), and Lamictal (lamotrigine). Other anticonvulsant medications are used off label very commonly in the treatment of bipolar disorder. This includ...

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   In support of this possibility, recent research suggests that disturbances in energy metabolism play a role in bipolar disorder, meaning the brain or certain parts of the brain may not be getting enough energy, at least from glucose. (1) This is often described as mitochondrial dysfunction. There appears to be a correlation between bipolar disorder...

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   There are case reports, which should be considered preliminary evidence (definitive evidence would be a blinded, randomized, controlled trial). In 2013, Phelps et al (2) described two women diagnosed with bipolar disorder, type II, whoeach did the ketogenic diet for over 2 years, were able to get off all of their psychiatric medications, and report...

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   As much as I wish it were that simple, it’s not. First of all, the version of the diet that appears to work for serious psychiatric disorders is the strict medical version (2:1 up to a 4:1 ratio diet), the same one used in treating epilepsy. This version of the diet should be medically prescribed and monitored, as it is very difficult to do and has...

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   Clay, H.B., Sillivan, S., Konradi, C., 2011. Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia. Int. J. Dev. Neurosci. 29, 311–324.

   Phelps et al, The ketogenic diet for type II bipolar disorder. Neurocase. 2013;19(5):423-6

   Palmer, CM. Ketogenic diet in the treatment of schizoaffective disorder: Two case studies. Schizophrenia Research, Volume 189 , 208 – 209

   Yaroslovsky et al, Ketogenic Diet in Bipolar Illness. Bipolar Disorders 2002: 4: 75

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5. pmc.ncbi.nlm.nih.gov › articles › PMC9299263The Ketogenic Diet for Refractory Mental Illness: A ...

   pmc.ncbi.nlm.nih.gov › articles › PMC9299263

   Primary psychiatric diagnoses were bipolar disorder type two (n = 13), schizoaffective disorder (n = 12), and major depressive disorder (n = 7). All participants had at least one indicator of poor metabolic health, such as overweight, obesity, hypertension, and/or elevated fasting blood glucose.

6. pubmed.ncbi.nlm.nih.gov › 39234289The effects of ketogenic metabolic therapy on mental health ...

   pubmed.ncbi.nlm.nih.gov › 39234289

   Aug 21, 2024 · Objectives: to investigate the effects of nutritional ketosis via a modified ketogenic diet (MKD) over 14 weeks in stable community patients with bipolar disorder, schizoaffective disorder, or schizophrenia.

7. www.sciencedirect.com › science › articleKetogenic Diet Intervention on Metabolic and Psychiatric ...

   www.sciencedirect.com › science › article

   May 1, 2024 · Taken together, our results show that a ketogenic diet intervention is a feasible and acceptable supplemental treatment to neuroleptic medications in an outpatient, real–world cohort, showing psychiatric and metabolic health improvements in those with bipolar or schizophrenia illness with co–morbid metabolic abnormalities.

8. pmc.ncbi.nlm.nih.gov › articles › PMC7387764Ketogenic Therapy in Serious Mental Illness: Emerging Evidence

   pmc.ncbi.nlm.nih.gov › articles › PMC7387764

   The first suggestive clinical evidence for the potential efficacy of the ketogenic diet in psychotic disorders emerged 55 years ago in a small, open-label, uncontrolled trial in 10 women hospitalized with schizophrenia. The ketogenic diet was added to their existing treatment for 4 weeks.