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  2. Androgenetic alopecia (AGA) in men is the most common type of hair loss in the US, affecting 50% of men by age 50 and up to 90% of men in their lifetime.

  3. Nov 6, 2021 · A randomized, double‐blind, placebo‐controlled trial to determine the effectiveness of botanically derived inhibitors of 5alphareductase in the treatment of androgenetic alopecia. J Altern Complement Med. 2002; 8 (2):143‐152. [Google Scholar]

  4. 5-alpha reductase inhibitors can treat male pattern baldness (androgenetic alopecia) and benign prostatic hyperplasia (BPH). BPH is a prostate condition that causes the prostate to enlarge, and it can lead to issues like erectile dysfunction and urinary problems.

  5. Per our objective, we had 4 outcomes of interest: change in total and terminal hair count after 24 and 48 weeks of therapy. A study was eligible for quantitative analyses if it investigated the therapeutic outcomes associated with monotherapy with minoxidil, dutasteride, and finasteride for male AGA.

  6. May 11, 2023 · Finasteride is a member of a class of drugs known as 5-alpha-reductase inhibitors. These drugs block the enzyme 5-alpha-reductase, thus blocking the conversion of testosterone to its active form dihydrotestosterone (DHT). Finasteride is a type II 5-alpha-reductase inhibitor and dutasteride blocks both type I and type II.

  7. May 9, 2024 · Our updated analyses of the up-to-date evidence regarding monotherapies for male AGA showed that the oral form of 5-alpha reductase inhibitors are more effective than oral minoxidil and other newer agents like Botox, microneedling, and photobiomodulation.

  8. While there are different treatments to stop hair loss and improve hair density, the 5-alpha reductase inhibitors have demonstrated to be effective in improving androgenetic alopecia in men and can maintain a positive response for many years.

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