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Aug 27, 2024 · Ibuprofen can cause internal bleeding, particularly in the stomach or intestines, especially with long-term or high-dose use. ... NSAIDs can cause potentially severe gastrointestinal bleeding ...
- Serious Side Effects of Ibuprofen
- Other Side Effects of Ibuprofen
- For Healthcare Professionals
- Frequently Asked Questions
- Further Information
Along with its needed effects, ibuprofen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediatelyif any of the following side effects occur while taking ibuprofen:
Some side effects of ibuprofen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the foll...
Applies to ibuprofen: compounding powder, intravenous solution, oral capsule, oral suspension, oral tablet, oral tablet chewable.
Ibuprofenside effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some side effects may not be reported. You may report them to the FDA. Medical Disclaimer
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Non-steroidal anti-inflammatory drugs (NSAIDs) are used commonly but can cause foregut symptoms, peptic ulcer disease and small bowel enteropathy. Such iatrogenic injury can be complicated by gastrointestinal bleeding and perforation. Limiting NSAID use or co-administration with proton pump inhibitors (PPIs) reduce dyspepsia, peptic ulcer ...
These complications include bleeding gastric or duodenal ulcers and, to a lesser extent, obstructions and perforations.12 In a retrospective analysis of a rheumatoid arthritis patient database published in 2000, OTC ibuprofen and naproxen users had a relative risk for serious GI complications of approximately 3.5 compared with NSAID nonusers,13 and it is estimated that 1%–2% of continuous ...
Jan 13, 2023 · Takeaway. Long-term ibuprofen use can increase your risk of bleeding and ulcers in your stomach and intestines. If you take ibuprofen regularly, you can take steps to prevent peptic ulcers and ...
- Crystal Raypole
Nov 1, 2005 · Summary: People who take high doses of ibuprofen on a regular basis are three times more likely to experience gastrointestinal (GI) bleeding than those who do not take painkillers. Results of a ...
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Dec 10, 2021 · The black box warning for NSAIDs related to gastrointestinal risk reads as follows, in an example from the labeling for the NSAID naproxen (Naprosyn®): NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.
