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  1. Nov 22, 2019 · The critical balance of oxygen in human cells is regulated by an intricate oxygen-sensing process in the body. When cancer cells hijack the process, they can fuel their own growth, and gain the ability to metastasize and resist chemotherapy and radiation treatment.

    • Dana-Farber Staff

      Uterine cancer ­­— also known as endometrial cancer — has...

  2. Nov 7, 2019 · Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.

  3. Jan 1, 2020 · Can oxygen therapy treat cancer? Another unproven idea about oxygen and cancer is that, since many tumors thrive in oxygen-deprived (hypoxic) conditions, giving cancer cells extra oxygen might shut them down or even kill them.

  4. Jun 26, 2018 · Cancer cells also need oxygen to survive, which is one reason why tumors make new vessels that tap into the body's blood supply, a process called angiogenesis. As tumors quickly develop, they outgrow their oxygen supply, but surprisingly, that does not always inhibit their growth.

  5. Jul 10, 2023 · For most of our tissues and cells, a lack of oxygen, or hypoxia, is bad news. However, cancer cells can thrive in these conditions, rendering tumors less susceptible to anti-cancer treatments including radiation. Now, new research may offer a way to break through cancer’s hypoxia-induced defenses.

  6. During the last century, it has been established that regions within solid tumors experience mild to severe oxygen deprivation, due to aberrant vascular function. These hypoxic regions are associated with altered cellular metabolism, as well as increased resistance to radiation and chemotherapy.

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  8. Mar 1, 2012 · As tumours rapidly grow and expand, the network of blood vessels bringing oxygen to their cells can’t keep up, leaving some cells starved of oxygen, or ‘hypoxic’. This would kill normal cells, but cancer cells have evolved to beat these conditions by switching on a protein called hypoxia-inducible factor (HIF), which in turn switches on ...

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