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Oct 2, 2019 · This has led to the hypothesis that blocking the import of glucose and the metabolism of glutamine could serve as powerful weapons against cancer. In other words, starving cancer cells of their favorite foods could inhibit tumor growth.
- Cell Biology
Starving Cancer by Cutting Off Its Favorite Foods, Glucose...
- Chemotherapy
Starving Cancer by Cutting Off Its Favorite Foods, Glucose...
- Cell Biology
Apr 24, 2019 · Like all cells, cancer cells need nutrients to grow. Sugar is one important fuel, but it’s far from cancer’s only requirement. Current research is aimed at targeting cancer’s dependence on the amino acid glutamine as a weakness.
Because starvation is one of the most efficient ways to promote autophagy in most cells [74], and in cancer mouse models it improves immunosurveillance and cancer treatment [65, 75], it will be important to study further the role of autophagy in the effects of fasting on cancer cells.
Understanding how these trafficking decisions are made and de-regulated in cancer cells could expose new ways to target cancer metabolism by attacking the supply wagons.
- Elizabeth M. Selwan, Brendan T. Finicle, Seong M. Kim, Aimee L. Edinger
- 10.1002/1873-3468.12121
- 2016
- 2016/04
Jan 5, 2024 · Now scientists and clinicians at Cedars-Sinai are exploring whether fasting diets, in conjunction with conventional cancer treatment, can help stall disease progression for even the most aggressive tumors, while reducing the toll on the body’s healthy, disease-fighting cells.
Oct 22, 2024 · Cutting off cancer cells' access to fat may help a specific type of cancer treatment work more effectively, reports a new study. The findings lay the groundwork for developing tailored dietary...
Oct 28, 2024 · Low amino acid availability can be lethal to cancer cells, so starving cancer cells initiate adaptive responses to nutrient deprivation that go beyond angiogenesis.
