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Jan 3, 2020 · Background The role of oxygen therapy in end-of-life care for patients with advanced cancer is incompletely understood. We aimed to evaluate the association between oxygen use and survival in patients with advanced cancer and low oxygen saturation in home care. Methods We conducted a retrospective cohort study at a primary care practice in suburban Tokyo. Adult patients in home care with ...
- Hiroshi Igarashi, Motoharu Fukushi, Naoki Nago
- 2020
Nov 22, 2019 · A key component of the body’s oxygen-sensing system is a set of molecular hypoxia-inducible factors, or HIFs, which can respond to a need for more oxygen by turning on genes and proteins that recruit new networks of blood vessels. Cancer cells in a growing tumor can adapt to oxygen deprivation by hijacking these HIFs.
Jan 1, 2020 · A key component of the body’s oxygen-sensing system is a set of molecular hypoxia-inducible factors, or HIFs, which can respond to a need for more oxygen by turning on genes and proteins that recruit new networks of blood vessels. Cancer cells in a growing tumor can adapt to oxygen deprivation by hijacking these HIFs.
Jun 26, 2018 · The answers are still not definitive, but some have used the unknowns to fuel unsupported claims that certain types of oxygen therapies, including hyperbaric oxygen (HBO) therapy, can cure cancer. “A lot of people have used myths in a bad way to promise hope to cancer patients who are seeking hope and have not been given any hope in order to ...
The benefit of supplemental oxygen for relief of breathlessness (palliative oxygen therapy) and for improving physical capacity and activity in daily life has not been established.98–100 While supplemental oxygen is indicated in patients with chronic severe hypoxaemia (partial pressure of oxygen (PaO 2) <7.4 kPa or peripheral oxygen saturation (SpO 2) <89% at rest) to prolong life,101 oxygen ...
Jun 7, 2022 · Oxygen therapy may be required in their course of management, not only for tiding over crises but also in end-of-life care. The typical indications for oxygen include hypoxia and dyspnea. In end-stage cancer patients, especially in lung cancer, the prime aim is to abolish dyspnoea and improve patient comfort [34].
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Nov 30, 2022 · Published systematic reviews and meta-analyses of palliative oxygen in cancer patients have limitations as they mostly include short-term trials in non-hypoxemic patients. 10,11 The largest randomized trial of palliative oxygen in relief of dyspnea in patients with refractory dyspnea is a long-term, multicenter double-blinded randomized controlled trial that compared oxygen 2 L per minute vs ...
