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Jun 27, 2018 · IHL were detrimental to both sexes with sex-specific differences in associations between IHL and cardiometabolic risk markers. This suggests that detailed anatomic and functional imaging, rather than BMI, provides a more complete understanding of metabolic risk associated with sex differences in fat distribution.
- Melanie Schorr, Laura E. Dichtel, Anu V. Gerweck, Ruben D. Valera, Martin Torriani, Karen K. Miller,...
- 2018
These differences are likely due to the impact of sex steroid hormones on body composition, fat distribution, and energy metabolism and are attenuated with increased age and menopause . The major proposed underlying mechanism of obesity-induced hypertension is the activation of the sympathetic nervous system, however, obesity seems to increase sympathetic nerve activity (SNA) in males but not ...
Mar 4, 2022 · Background Beyond the degree of adiposity, the pattern of fat distribution has a profound influence on cardiometabolic risk. It is unclear if sex differences in body fat distribution can potentially explain any sex differences in the prevalence of the metabolic syndrome (MetS) and in individual cardiometabolic risk factors among obese men and women. Methods In this cross-sectional analysis ...
- Christina Strack
Nov 21, 2019 · This review focuses on the human genetics, epidemiology, and molecular pathophysiology of sex differences in central obesity, adipose distribution, and related cardiometabolic disorders. Distribution of fat is important for cardiometabolic health, with peripheral fat depots having a protective effect and central visceral fat depots conferring a detrimental effect on health. There are important ...
- Heidi S. Lumish, Marcella O’Reilly, Muredach P. Reilly
- 2020
Jan 1, 2016 · The regulators of sex differences in fat-depot distribution and their influence on the development of metabolic disorders are not fully understood, but evidence from human and animal studies suggests a predominant role of sex hormones, particularly estrogens and androgens (Fig. 9.2) [15], [16].
- Kelly Ethun
- 2016
Feb 23, 2021 · However, it has been shown that trunk fat estimated by DXA has greater correlation with total abdominal fat than visceral fat. 13, 14 On the other hand, gluteofemoral fat is associated with a protective lipid and glucose profile and decrease in cardiovascular and metabolic risk. 15, 16, 17 To understand sex differences in the relative effects of trunk and leg fat on cardiovascular risk, we ...
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Do sex differences in fat distribution affect metabolic risk?
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Are sex-specific differences in fat distribution associated with cardiometabolic risk markers?
Do sex steroids affect body fat deposition and metabolic disease risk?
Aug 8, 2017 · MetSyn is defined by the presence of three of the following five risk factors: abdominal obesity, elevated triglyceride levels, low high density lipoprotein (HDL) cholesterol levels, high blood pressure (hypertension), and elevated fasting blood glucose levels (73). Sex differences exist in nearly all of the components of MetSyn (Figure 1).
