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Jan 1, 2016 · The impact of sex steroids on body fat distribution, however, is complicated by the metabolism of sex steroids. The liver synthesizes and releases sex hormone-binding globulin (SHBG), which binds circulating estrogen and testosterone. Decreased SHBG levels may be associated with an android body composition [41]. Thus, future studies need to ...
- Kelly Ethun
- 2016
Oct 14, 2016 · The sex-specific variations in body fat distribution appear to be at least partially regulated by sex steroids via effects on FA metabolism specific to certain depots. There is little evidence to support a role for defective lipolysis as a contributor towards fat gain in one depot vs. another in men and women.
- Sylvia Santosa, Michael D. Jensen
- 2014
Jul 18, 2023 · It has been well established that the distribution of regional body fat is a more important risk factor for cardiovascular disease than the total amount of body fat . Specifically liver fat and visceral adipose tissue (VAT) are associated with insulin resistance and metabolic and cardiovascular disease risks (2, 4). Both liver fat and visceral ...
- 10.1210/clinem/dgad409
- 2024/01
In contrast, administration of testosterone to female-to-male transsexual individuals results in a reduction in subcutaneous fat area on MRI with a modest increase in visceral fat area. 8,9 The importance of sex steroids in adipose tissue metabolism and regional adiposity has been studied in vitro using isolated adipocytes, in studies of animals after gonadectomy with or without hormone ...
Mar 5, 2018 · As abdominal fat is a risk factor for the development of metabolic syndrome, type 2 diabetes mellitus and cardiovascular disease , abdominal adiposity and the ensuing hyperinsulinemia can ...
- Zihong He, Tuomo Rankinen, Arthur S. Leon, James S. Skinner, André Tchernof, Claude Bouchard
- 2018
Aug 21, 2021 · Visceral adiposity predicts adverse cardiovascular risk factor profiles in children 1 , 2 as well as adults. 3 Therefore, understanding the determinants of visceral adipose tissue (VAT) in youth is important to improving metabolic health. Although endogenous sex steroids predict VAT area in adults, 4 such an association has not been established ...
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Do sex steroids affect body fat distribution?
Do steroid hormones affect body composition and fat distribution?
Do steroid hormones influence body fat?
Are baseline steroid levels associated with body composition and fat distribution?
How do sex steroids affect adipokine expression?
May 21, 2022 · Estrogen may help protect from VAT and ectopic fat deposition, instead promoting subcutaneous fat storage while protecting skeletal muscle from damage by reducing inflammation and oxidant production . Sex steroids also influence endocrine function of adipose tissue, which impacts whole body metabolism.
