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1. www.dermatologyadvisor.com › news › maintenanceMaintenance Therapy Is Needed After Hair Regrowth With ...

   www.dermatologyadvisor.com › news › maintenance

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   Sep 26, 2024 · The results of this trial suggest that severe alopecia areata is a relapsing condition requiring maintenance therapy after successful regrowth has been achieved. The study included 654 patients, of whom 281 (43%) received 4 mg and 184 (28%) received 2 mg through week 52, at which point 115 (41%) patients taking baricitinib 4 mg and 39 (21% ...

2. www.ncbi.nlm.nih.gov › pmc › articlesEfficacy and Safety of Baricitinib in Patients with Severe ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Alopecia areata (AA) is an autoimmune disorder causing non-scarring hair loss on the scalp, face, and body. Severe AA (≥ 50% scalp hair loss) is unlikely to remit without treatment, with only 3.3–6.2% of patients achieving ≥ 80% scalp hair coverage with placebo in recent 36-week trials [ 1 ].

   • DOI: 10.1007/s40257-023-00764-w
   • Published: 2023

   • Publication: Am J Clin Dermatol. 2023; 24(3): 443-451.

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4. www.ajmc.com › view › long-term-efficacy-ofLong-Term Efficacy of Baricitinib for Severe Alopecia Areata

   www.ajmc.com › view › long-term-efficacy-of

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   Aug 30, 2024 · Baricitinib is an oral Janus kinase (JAK) inhibitor that has been found to be more effective than established therapies for moderate to severe alopecia areata. 2 However, alopecia areata is a ...

5. www.jaad.org › article › S0190-9622(24)02037-149690 Long-term efficacy of baricitinib in alopecia areata: 3 ...

   www.jaad.org › article › S0190-9622(24)02037-1

   Introduction: This analysis evaluates long-term efficacy over three years of continuous therapy in baricitinib 4mg and 2mg Week 52 (W52) responders (SALT score ≤20 (≤20% scalp hair loss)) with severe alopecia areata (AA).

6. academic.oup.com › bjd › articleWhen to expect scalp hair regrowth during treatment of severe ...

   academic.oup.com › bjd › article

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   Sep 14, 2023 · Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss involving any hair-bearing site; it ranges in severity from one or a few patches to total loss of hair on the scalp and/or body. 1 The loss of the hair follicle immune privilege leads to premature termination of the anagen phase and entry into catagen phase. 2 By blocking intracellular signalling of key ...

7. onlinelibrary.wiley.com › doi › 10A new era for alopecia areata: New treatments and improved ...

   onlinelibrary.wiley.com › doi › 10

   Feb 23, 2024 · These data show that long-term treatment with baricitinib is necessary to maintain results in responders and that results of treatment in partial responders improve in time, as in this group of patients a meaningful hair regrowth can be achieved slowly, over a period di 54–72 weeks.

8. People also ask

   Does baricitinib help alopecia areata?

   • In two phase III trials, efficacy of baricitinib for severe alopecia areata continued to improve over 52 weeks. Alopecia areata (AA) is an autoimmune disorder causing non-scarring hair loss on the scalp, face, and body.

   Efficacy and Safety of Baricitinib in Patients with Severe Alopecia

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9974384/

   See all results for this question

   Does baricitinib increase hair regrowth?

   • In two independent phase III trials of adults with severe AA, the proportions of patients achieving scalp hair, eyebrow, and eyelash regrowth increased over 52 weeks of treatment with once-daily oral baricitinib.

   Efficacy and Safety of Baricitinib in Patients with Severe Alopecia

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9974384/

   See all results for this question

   Does baricitinib cause hair loss?

   • In BRAVE-AA1, 40.9% of patients who took baricitinib 4 mg and 21.2% of patients who took baricitinib 2 mg had 20% or less missing scalp hair by Week 52. Similarly, in BRAVE-AA2, 36.8% of patients who took baricitinib 4 mg and 24.4% of patients who took baricitinib 2 mg had 20% or less missing scalp hair by Week 52.

   Efficacy and Safety of Baricitinib in Patients with Severe Alopecia

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9974384/

   See all results for this question

   How effective is Janus kinase inhibitor baricitinib for severe alopecia areata?

   • The oral Janus kinase inhibitor baricitinib has demonstrated efficacy for adults with severe alopecia areata (≥ 50% scalp hair loss) over 36 weeks. In two phase III trials, efficacy of baricitinib for severe alopecia areata continued to improve over 52 weeks.

   Efficacy and Safety of Baricitinib in Patients with Severe Alopecia

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9974384/

   See all results for this question

   Can alopecia areata remit without treatment?

   • Alopecia areata (AA) is an autoimmune disorder causing non-scarring hair loss on the scalp, face, and body. Severe AA (≥ 50% scalp hair loss) is unlikely to remit without treatment, with only 3.3–6.2% of patients achieving ≥ 80% scalp hair coverage with placebo in recent 36-week trials [ 1 ].

   Efficacy and Safety of Baricitinib in Patients with Severe Alopecia

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9974384/

   See all results for this question

9. www.aafp.org › pubs › afpBaricitinib (Olumiant) for the Treatment of Alopecia Areata

   www.aafp.org › pubs › afp

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   Baricitinib. Initial dosage: 2 mg once daily. Tablets: 1 mg, $2,770 (1-mg and 2-mg tablets) (Olumiant) If hair growth does not occur, increase to 4 mg once daily. 2 mg, 4 mg. $5,530 (4-mg tablets ...