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  1. The refinement and maturation of the central nervous system over this prolonged period, however, makes the adolescent brain highly susceptible to perturbations from acute and chronic drug exposure. Here we review the preclinical literature addressing the long-term consequences of adolescent exposure to common recreational drugs and drugs-of-abuse.

  2. This article reviews the extant literature on neurocognition, brain structure, and brain function in adolescent substance users with an emphasis on the most commonly used substances, and in the context of ongoing neuromaturational processes. Methodological and treatment implications are provided.

  3. Oct 6, 2023 · Article 27 November 2021. Adolescence is a period of critical development in the brain and body. Developmental changes in the brain lead to adolescents exhibiting heightened impulsiveness,...

  4. Drugs also favor the more animalistic part of the brain called the amygdala — which stimulates anxiety, irritability, and unease — rather than the more rational frontal cortex. “Drug use creates challenges for developing into a balanced and happy adult from the start,” Dr. Lane says.

  5. Aug 16, 2018 · Unfortunately, neurobiological development during adolescence can be influenced by environmental factors such as drug exposure. Engaging in drug use during adolescence has been a long-standing health concern, especially how it predicts or relates to drug using behavior later in life.

    • Sean M. Mooney-Leber, Thomas J. Gould
    • 2018
  6. Jun 27, 2024 · Early use of alcohol and other substances can increase the likelihood of going on to use other drugs and of developing a substance use disorder. NIDA leads the Adolescent Brain Cognitive DevelopmentSM Study (ABCD Study ®), a long-term study of brain development and child health.

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  8. Feb 26, 2024 · Abstract. The increased frequency of risk taking behavior combined with marked neuromaturation has positioned adolescence as a focal point of research into the neural causes and consequences of...

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