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  1. Aug 4, 2020 · Future prospective longitudinal studies (e.g., the on-going Adolescent Brain Cognitive Development Study of the National Institute on Drug Abuse) looking at the markers of neurobiological function (e.g., brain imaging) before the appearance of substance use could help uncover the mechanistic underpinnings of the long-term consequences of substance use that have been reviewed here.

  2. Feb 24, 2014 · Alcohol and marijuana use are common. Recent research has indicated that adolescent substance users show abnormalities on measures of brain functioning, which is linked to changes in neurocognition over time. Abnormalities have been seen in brain structure volume, white matter quality, and activation to cognitive tasks, even in youth with as ...

    • L. M. Squeglia, J. Jacobus, Susan F. Tapert
    • 10.1177/155005940904000110
    • 2009
    • 2009/01
  3. Jun 27, 2024 · Teens may experiment with nicotine via cigarettes or vaping, alcohol, and marijuana, at a time when exposure to these substances can have a significant impact on brain development. Early use of alcohol and other substances can increase the likelihood of going on to use other drugs and of developing a substance use disorder.

  4. Overall, adolescent alcohol use has been found to negatively affect cognition, brain structure, and function (Table 1); however, the level to which alcohol use and different patterns of drinking affects male and female brain functioning has been debated. Research in this field is also limited to natural observational studies, and it is common for a portion of adolescents to use multiple ...

    • Briana Lees, Lindsay R. Meredith, Anna E. Kirkland, Brittany E. Bryant, Lindsay M. Squeglia
    • 10.1016/j.pbb.2020.172906
    • 2020
    • 2020/05
    • Patterns of Adolescent Drinking
    • Relationship Among Adolescent Risk-Taking, Brain Plasticity, and Drinking
    • Immediate Effects of Alcohol on The Brain and Behavior
    • Longer-Term Effects of Alcohol on The Brain and Behavior
    • What Can We do?

    People often begin to drink alcohol and use other substances during adolescence. According to the 2023 National Survey on Drug Use and Health (NSDUH), about 33.1% of people ages 12 to 20—or 12.6 million—reported having tried alcohol at least once in their lifetime.1,2 Although adolescents tend to drink alcohol less often than adults, they tend to d...

    Adolescents are motivated to explore and take risks. These learning experiences, complemented by the adolescent brain’s increased ability to readily change in response to experiences (also known as brain plasticity), are key to developing the skills and knowledge to become independent. Although this increase in brain plasticity and risk-taking can ...

    In adults, drinking alcohol impairs decision-making and impulse control, and can lead to a range of negative consequences. For adolescents, drinking alcohol can make it even more difficult to control impulses and make healthy choices. In both adolescents and adults, drinking also compromises the ability to sense danger by disrupting the function of...

    In some people, a history of adolescent alcohol use could increase a person’s likelihood of developing alcohol use disorder and is associated with mental health disorders such as anxiety and depression during adolescence and later in life.9,10,11 More and more research suggests that drinking alcohol in adolescence may have significant effects on br...

    The more we know about how alcohol affects the adolescent brain, the more we can inform the conversations about alcohol that we have with teens. Parents and teachers play a major role in the way adolescents think about alcohol. Research demonstrates, for example, that children whose parents allow them to drink are more likely to quickly transition ...

  5. Feb 26, 2024 · The associations of comorbid substance use disorders and psychiatric conditions with adolescent brain structure and function: a review. J Neurol Sci. 2020;418:117099.

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  7. Aug 16, 2018 · During adolescence, the brain continues to undergo vital developmental processes. In turn, complex behavioral and cognitive skills emerge. Unfortunately, neurobiological development during adolescence can be influenced by environmental factors such as drug exposure. Engaging in drug use during adole …

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