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Lack of biological validity
- The lack of biological validity of the current classification systems of mental disorders, namely the World Health Organization’s (WHO) International Classification of Diseases (ICD-10) and the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-5), is considered to be one of the major reasons why psychiatry has made little progress in translating biomedical research findings into clinical practice.
bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-020-02541-zThe biological classification of mental disorders (BeCOME ...
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Does the classification system for mental disorders have a biological validity?
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How do diagnostic classification systems categorise mental psychopathology in mental disorders?
Are psychiatric classification systems reliable?
• Biology: very few psychiatric disorders have a biological basis that confirms clinical impressions of disease • ‘Zone of rarity’ between health and disease rarely present in psychiatric disorders
- Peter Tyrer
- 2014
May 11, 2020 · The compromised biological validity of the current classification system for mental disorders impedes rather than supports the development of treatments that not only target symptoms but also the underlying pathophysiological mechanisms.
- Tanja M. Brückl, Victor I. Spoormaker, Philipp G. Sämann, Anna-Katherine Brem, Anna-Katherine Brem, ...
- 2020
Dec 6, 2017 · We identify four key issues that present challenges to understanding and classifying mental disorder: etiology, including the multiple causality of mental disorder; whether the relevant phenomena are discrete categories or dimensions; thresholds, which set the boundaries between disorder and nondisorder; and comorbidity, the fact that ...
- Lee Anna Clark, Bruce Cuthbert, Roberto Lewis-Fernández, William E. Narrow, Geoffrey M. Reed
- 2017
Abstract. As advances in neuroscience and genetics reveal complex associations between brain structures, functions and symptoms of mental disorders, there have been calls for psychiatric classifications to be reconfigured, to conceptualize mental disorders as disorders of the brain. In this paper, I argue that this view is mistaken, and that ...
Jun 9, 2020 · The omission of biological markers means that psychiatric diagnosis is still primarily based on the symptoms and course of a disorder. An additional main aim of DSM-5 was to use a dimensional diagnostic system, i.e., a syndrome-based approach, instead of or in addition to a categorical diagnostic system [25].
- Hans-Jürgen Möller
- hans-juergen.moeller@med.uni-muenchen.de
- 2020
Jan 1, 2022 · Diagnostic classification systems categorise mental psychopathology in mental disorders. Although these entities are clinical constructs developed by consensus, it has been pointed out that in practice they are usually managed as natural entities and without evaluating aspects related to their nosological construction.
Mar 14, 2023 · The difficulties with current classification systems and the lack of success of biological approaches to psychiatry have led to new proposals for changing and/or theorizing about the nature, study, and classification of mental disorders in the long run. Three such approaches will be presented here. 9.5.1 Research Domain Criteria (RDoc)
