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- The osteoblasts secrete a collagen-proteoglycan matrix that is able to bind calcium salts. Through this binding, the prebone (osteoid) matrix becomes calcified. In most cases, osteoblasts are separated from the region of calcification by a layer of the osteoid matrix they secrete.
Conversely, osteoblasts, another type of bone cell, deposit calcium and phosphate into bone tissue when blood calcium levels are high, reducing the amount of calcium circulating in the bloodstream. This intricate process is highly regulated by various hormones and signaling pathways (one of the most important hormones involved in this ...
- Osteogenesis: The Development of Bones
Through this binding, the prebone (osteoid) matrix becomes...
- Osteogenesis: The Development of Bones
Oct 30, 2023 · Osteoprogenitor cells brought to the developing bone through the periosteal buds divide, forming more osteoprogenitor cells. Some of these cells will differentiate into osteoblasts that will continue to form bone matrix on the surface of the calcified cartilage.
- Julie Doll
- Content Manager
The osteoblasts secrete osteoid, uncalcified matrix consisting of collagen precursors and other organic proteins, which calcifies (hardens) within a few days as mineral salts are deposited on it, thereby entrapping the osteoblasts within. Once entrapped, the osteoblasts become osteocytes (Figure 6.4.1 b).
- Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
- 2019
Through this binding, the prebone (osteoid) matrix becomes calcified. In most cases, osteoblasts are separated from the region of calcification by a layer of the osteoid matrix they secrete. Occasionally, though, osteoblasts become trapped in the calcified matrix and become osteocytes —bone cells.
- Scott F Gilbert
- 2000
- 2000
Jul 14, 2023 · Introduction. A remarkable cascade of biological events takes place from mesenchymal condensation during early embryonic development to postnatal maturation, providing the body with the skeletal system for structural support and stability, mineral storage, and protection of vital organs.
The osteoblasts secrete osteoid, uncalcified matrix, which calcifies (hardens) within a few days as mineral salts are deposited on it, thereby entrapping the osteoblasts within. Once entrapped, the osteoblasts become osteocytes (Figure 1 b).
Jul 30, 2022 · Most of the chondrocytes in the zone of calcified matrix, the zone closest to the diaphysis, are dead because the matrix around them has calcified. Capillaries and osteoblasts from the diaphysis penetrate this zone, and the osteoblasts secrete bone tissue on the remaining calcified cartilage.
