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  1. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
  2. Oct 30, 2023 · Endochondral ossification occurs in the long bones around the 6th embryonic week. It involves the formation of hyaline cartilage precursors from aggregated mesenchymal cells , and their subsequent systematic replacement by bone to form the growing skeleton.

    • Content Manager
    • 14 min
  3. The initiation of endochondral ossification starts by proliferation and condensation of mesenchymal cells in the area where the bone will eventually be formed. Subsequently, these mesenchymal progenitor cells differentiate into chondroblasts, which actively synthesize cartilage matrix components.

  4. Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.

  5. Apr 9, 2024 · Bone ossification is the formation of new bone, which can occur in two ways: intramembranous ossification and endochondral ossification. This article will discuss both forms as well as clinically relevant examples.

  6. May 1, 2023 · Endochondral ossification begins with mesenchymal tissue transforming into a cartilage intermediate, which is later replaced by bone and forms the remainder of the axial skeleton and the long bones. Bone ossification, or osteogenesis, is the process of bone formation.

  7. May 13, 2022 · Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.

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