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  1. Jul 17, 2023 · Cardiac output (CO) is the amount of blood pumped by the heart minute and is the mechanism whereby blood flows around the body, especially providing blood flow to the brain and other vital organs. The body’s demand for oxygen changes, such as during exercise, and the cardiac output is altered by modulating both heart rate (HR) and stroke volume (SV). As a result, the regulation of cardiac ...

    • Jordan King, David R. Lowery
    • 2023/07/17
    • 2019
    • Cardiac Output. Cardiac output is the volume of blood flow from the heart through the ventricles, and is usually measured in litres per minute (L/min). Cardiac output can be calculated by the stroke volume multiplied by the heart rate.
    • Peripheral Vascular Resistance. Peripheral vascular resistance refers to compliance, which is the ability of any compartment to expand to accommodate increased content.
    • Volume of Circulating Blood. Volume of circulating blood is the amount of blood moving through the body. Increased venous return stretches the walls of the atria where specialized baroreceptors are located.
    • Viscosity of Blood. Viscosity of blood is a measure of the blood’s thickness and is influenced by the presence of plasma proteins and formed elements in the blood.
  2. Jul 30, 2022 · Cardiac output; Compliance; Volume of the blood; Viscosity of the blood; Blood vessel length and diameter; Recall that blood moves from higher pressure to lower pressure. It is pumped from the heart into the arteries at high pressure. If you increase pressure in the arteries (afterload), and cardiac function does not compensate, blood flow will ...

  3. Blood flow refers to the movement of blood through a vessel, tissue, or organ, and is usually expressed in terms of volume of blood per unit of time. It is initiated by the contraction of the ventricles of the heart. If we consider the entire cardiovascular system, blood flow equals cardiac output.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
    • Overview
    • Test Details
    • Results and Follow-Up

    Cardiac output, or how much blood your heart can pump in a minute, can tell your healthcare provider about your heart’s strength and health. This can help them make a diagnosis or find out if your treatment is working as it should. Providers can use several methods to calculate cardiac output. Some methods are more invasive than others.

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    OverviewTest DetailsResults and Follow-Up

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    How to calculate cardiac output

    Your healthcare provider can use several different methods to figure out your cardiac output. These methods include: Find out the amount of oxygen an organ or tissue uses by subtracting how much oxygen is in your veins from how much oxygen is in your arteries. Then you multiply it by blood flow rate. Compare the temperature of blood in your vena cava or right atrium with the temperature of blood in your pulmonary arteries. Take mean arterial pressure (your arteries’ average pressure) and divide it by systemic vascular resistance (the amount of force or pressure your vessels put on your blood). Use a portable device that involves breathing certain gases through a mouthpiece. Use a device that involves putting six electrodes on your chest. These measure your heart rate and stroke volume and calculate cardiac output from those. Transthoracic echocardiography to estimate stroke volume. Heart MRI. Inject dye into your blood when it goes into your heart’s right side and measure how much dye comes out of your heart’s left side. Advertisement

    What to expect during the test

    For the most accurate method, your provider will need to measure how much oxygen you’re breathing in and get blood samples from an artery and from a catheter in your pulmonary artery. Your provider can do this during right heart catheterization. You will be able to find out your cardiac output the same day along with information regarding pressures inside your heart. Care at Cleveland Clinic Cardiology Care Cardiology Care for Children Make an Appointment

    What type of results do you get and what do the results mean?

    Normal cardiac output ranges from 5 to 6 liters per minute in a person at rest. While exercising, an athlete can have a cardiac output of more than 35 liters per minute. A non-athlete’s cardiac output will be lower than an athlete’s but higher than when the non-athlete is at rest. Your cardiac output also goes up during pregnancy.

  4. Venous Return - Hemodynamics. Venous return (VR) is the flow of blood back to the heart. Under steady-state conditions, venous return must equal cardiac output (CO) when averaged over time because the cardiovascular system is essentially a closed loop (see figure). Otherwise, blood would accumulate in either the systemic or pulmonary circulations.

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  6. Figure 19.4.1 – Major Factors Influencing Cardiac Output: Cardiac output is influenced by heart rate and stroke volume, both of which are also variable. SVs are also used to calculate ejection fraction, which is the portion of the blood that is pumped or ejected from the heart with each contraction.

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